Results 151 to 160 of about 229,451 (392)

Les formes de la separation dans les Lettres persanes

open access: yesRevista Criação & Crítica, 2017
Cet article aborde la thématique de la séparation dans le dispositif romanesque des Lettres persanes, de Montesquieu, à savoir, le roman du sérail. De ce fait, cette étude entend analyser les formes de la séparation qui aparaissent dans les lettres des ...
Thaïs Chauvel
doaj   +1 more source

Negative regulation of the androgen receptor gene through a primate specific androgen response element present in the 5' UTR [PDF]

open access: yes, 2014
Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Hay, Colin W   +5 more
core   +2 more sources

TMB‐High, MSI‐High Castration‐Resistant Prostate Cancer Treated With Pembrolizumab

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction The use of pembrolizumab in patients with microsatellite instability‐high (MSI‐high) and tumor mutation burden‐high (TMB‐high) prostate cancer in Japan is not widely reported. Here, we report the case of a patient with MSI‐high and TMB‐high prostate cancer who responded well to pembrolizumab after multiple systemic treatments ...
Satoshi Muraoka   +8 more
wiley   +1 more source

Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. [PDF]

open access: yes, 2007
Peroxisome proliferator-activated receptor (PPAR)alpha is a nuclear receptor that mediates gender differences in lipid metabolism. PPARalpha also functions to control inflammatory responses by repressing the activity of nuclear factor kappaB (NF-kappaB ...
Baranzini, Sergio E   +9 more
core  

Atezolizumab with enzalutamide versus enzalutamide alone in metastatic castration-resistant prostate cancer: a randomized phase 3 trial

open access: yesNature Network Boston, 2022
T. Powles   +19 more
semanticscholar   +1 more source

Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer.

open access: yesCancer Research, 2018
The standard treatment for metastatic prostate cancer, androgen deprivation therapy (ADT), is designed to suppress androgen receptor (AR) activity. However, men invariably progress to castration-resistant prostate cancer (CRPC), and AR reactivation ...
Joshua W. Russo   +13 more
semanticscholar   +1 more source

Heart Failure Induced by Darolutamide in an Older Patient With M0 Castration‐Resistant Prostate Cancer: A Case Report

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Androgen receptor signaling inhibitors (ARSIs) improve survival in prostate cancer; however, it may increase cardiovascular risks, especially in elderly patients with heart disease. Case Presentation A 94‐year‐old man with aortic valve stenosis, hypertension, and diabetes had a nodal metastatic progression of prostate cancer at 88 
Yoshiyuki Miyaji   +2 more
wiley   +1 more source

Net requirements of energy, protein and macrominerals for weight gain of grazing beef cattle castrated at different ages, with and without supplementation

open access: yesRevista Brasileira de Zootecnia, 2012
The objective of this experiment was to estimate the requirements of energy, protein and macrominerals of grazing crossbreds calves, in Brachiaria decumbens Stapf pasture, castrated at different ages, with and without supplementation.
Anilza Andréia da Rocha   +7 more
doaj   +1 more source

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