Results 201 to 210 of about 77,635 (307)

Messenger RNA From Canine Cytology Lymph Node Specimens Can Be Utilised for Gene Expression Profiling Using Digital RNA Counting

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Gene expression profiling (GEP) is being used with increasing frequency to characterise canine tumours, but canine samples are often not collected in a medium to preserve RNA. Cytology samples from human tumours have been shown to provide adequate RNA for GEP using NanoString nCounter technology, suggesting a similar approach might be viable ...
McKenzie Olsen, Emily Rout, Kelly Hughes, Janna Yoshimoto, Anne Avery, R. Adam Harris   +5 more
wiley   +1 more source

Single-cell imaging analysis, therapeutic modeling and a Phase Ib trial validate BCL-2 as a target across heterogeneous castration-resistant prostate cancer. [PDF]

Signal Transduct Target Ther
Jamroze A, Liu X, Hou S, Jess Li W, Yu H, Tracz A, Jacobi J, Li Q, Nastiuk K, Chen X, Huang J, Lin K, Liu M, Cai C, Lu Y, Puzanov I, Kirk JS, Chatta G, Tang DG.   +18 more
europepmc   +1 more source

Establishment of Haemonetics TEG 6s Reference Interval in Healthy Dogs

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background A thromboelastogram viscoelastic monitor (the TEG 6s) has recently become available for use in veterinary patients. It is therefore necessary to establish reference intervals for the new device in each species where it is employed.
Kaylan Whetstone, Justin Heinz, Lonnie E. Grantham II, Michaela Stavropoulos, Chelsie Hall, Floris C. Dröes, Thomas H. Edwards   +6 more
wiley   +1 more source

Targeting oncogenic TβRI signaling inhibits androgen-independent prostate cancer growth and metastasis. [PDF]

Signal Transduct Target Ther
Flodbring Larsson P, Schmidt A, Mu Y, Zang G, Song J, Gajavilli V, Tao J, Rakhimova O, Ericsson M, Aripaka K, Halin Bergström S, Yuan W, Bogdan D, Zhang AH, Welti J, Bergh A, de Bono J, Heldin CH, Landström M.   +18 more
europepmc   +1 more source

Codocytosis in the Dog: 345 Cases (2020–2022)

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Introduction Codocytes, or target cells, are a morphologic variation of erythrocytes characterized by increased membrane surface area relative to volume. In dogs, codocytosis is frequently noted on blood smear evaluation, but its clinical significance remains poorly understood. Objectives To characterize the clinical conditions associated with
Sarena M. Krojanker, Maria Jaramillo, Brad D. Cingolani, Floyd L. Williams Jr., Priscila B. S. Serpa, Andrew D. Woolcock   +5 more
wiley   +1 more source

Correction: SLC7A11 upregulation via AR and NEDD4L ubiquitination contributes to ferroptosis inhibition and enzalutamide resistance in castration-resistant prostate cancer. [PDF]

Cell Death Dis
Tang M, Xue L, Wang B, Jiang Z, Li P, Bu H, Zhao C, Zhang Y, Liu S, Chen X, Liu B, Meng X, Li J.   +12 more
europepmc   +1 more source

Regression Using 20 Samples to Harmonize a Point‐of‐Care Analyzer With a Commercial Laboratory Analyzer for Feline Plasma Biochemistry Testing

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Harmonization enables direct comparison of patient results from different analyzers and/or measurement techniques and the use of common reference intervals and decision thresholds. Point‐of‐care analyzers (POC) cannot be calibrated by the end user, so regression offers an opportunity for calculated harmonization.
Randolph M. Baral, Bente Flatland, Susan M. Jaensch, Douglas A. Lessels, Kathleen P. Freeman   +4 more
wiley   +1 more source

Impact of the Nadir Androgen Receptor Signaling Inhibitor-Derived Integrative Response Model in Real-World Patients With Metastatic Castration-Sensitive Prostate Cancer. [PDF]

Prostate
Yukihiro K, Sekino Y, Goto K, Saito K, Fujiyama K, Kagiyama Y, Kurimura Y, Fukuoka K, Naito M, Miyamoto S, Kobatake K, Kitano H, Goriki A, Hieda K, Hinata N.   +14 more
europepmc   +1 more source

Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma

Veterinary Clinical Pathology, EarlyView.
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal, Samantha L. Sommer, Sarah Golconda, Eric T. Hostnik, Russell Sakacs, Janice Park, Ashley Potts, Ronaldo C. da Costa, Christopher Premanandan, Kara Corps, Sanggu Kim, Maxey L. Wellman   +11 more
wiley   +1 more source

Androgen receptor reactivation in castration-resistant prostate cancer: mechanisms, epigenetic adaptation, and therapeutic vulnerabilities. [PDF]

Front Oncol
Guo J, Wu K, Ma Z, Guo S, Wang F, Lu L.
europepmc   +1 more source