Results 261 to 270 of about 219,417 (396)

BRCA Mutation Testing in Men with Metastatic Castration‐Resistant Prostate Cancer: Practical Guidance for Australian Clinical Practice

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Molecular diagnostic testing identified mCRPC patients with BRCA mutations eligible for targeted therapies. Testing success is often contingent on the quality of tissue handling and laboratory processing techniques to minimize DNA degradation and suboptimal sequencing data quality.
Arun A. Azad   +4 more
wiley   +1 more source

Circulating microRNA profiles are associated with acute pain and stress in castrated and tail docked lambs. [PDF]

open access: yesVet Anim Sci
Farr RJ   +7 more
europepmc   +1 more source

E2F4 Promotes Malignant Behaviors of Prostate Cancer Through Activating MUC1 Expression Transcriptionally

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
E2F4 promotes malignant behaviors of prostate cancer through activating MUC1 expression transcriptionally. ABSTRACT Background The malignant features of prostate cancer (PC) threaten the patient's life. MUC1 was observably enhanced in PC. However, the reason for higher MUC1 expression in PC is still unclear and deserves to be further investigated ...
Long Cheng   +6 more
wiley   +1 more source

Evaluation of serum miR‐216a and miR‐375 as biomarkers in dogs with acute pancreatitis

open access: yesJournal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 92-100, January/February 2023., 2023
Abstract Background Serum microRNAs have emerged as biomarkers of various diseases. Overexpression of serum miR‐216a and miR‐375 occurs in dogs with experimentally induced acute pancreatitis (AP). Objectives To identify the possibility of using serum miR‐216a and miR‐375 as biomarkers for the diagnosis and evaluation of treatment response in dogs with ...
Dohee Lee   +7 more
wiley   +1 more source

Dexamethasone is a regulator of clock genes in testicular peritubular cells

open access: yesAndrology, EarlyView.
Abstract Background We recently found that peritubular cells of the human testis are a dominant site of expression of the glucocorticoid receptor (GR; encoded by NR3C1). Activation of GR by dexamethasone (Dex) strongly influences the phenotype of cultured human testicular peritubular cells (HTPCs), causing massive changes of their proteome and ...
Harald Welter   +11 more
wiley   +1 more source

Outcomes of 434 dogs with non‐steroidal anti‐inflammatory drug toxicosis treated with fluid therapy, lipid emulsion, or therapeutic plasma exchange

open access: yesJournal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 161-172, January/February 2023., 2023
Abstract Background Traditional management of non‐steroidal anti‐inflammatory drug (NSAID) intoxication includes gastrointestinal decontamination, intravenous administration of fluids (IVF), and gastroprotection. Intravenous administration of lipid emulsion (ILE) and therapeutic plasma exchange (TPE) are popular novel therapeutic strategies ...
Nolan V. Chalifoux   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy