Results 261 to 270 of about 229,451 (392)

Androgen Receptor‐Controlled microRNA‐124‐3p.2 Suppresses Prostate Cancer Progression via CCL2 Inhibition

Cancer Science, EarlyView.
We identified a novel mechanism where AR signaling suppresses CCL2 expression through miR‐124‐3p.2, which regulates cancer cell migration and progression. Patients with low miR‐124‐3p.2 and high CCL2 levels exhibited faster progression to castration‐resistant prostate cancer, highlighting the potential of the miR‐124‐3p.2–CCL2 axis as a therapeutic ...
Shuhei Aoyama, Kouji Izumi, Kaoru Hiratsuka, Takahiro Inaba, Yoshiki Koketsu, Ryunosuke Nakagawa, Ren Toriumi, Taiki Kamijima, Hiroshi Kano, Tomoyuki Makino, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Shohei Kawaguchi, Kazuyoshi Shigehara, Takahiro Nohara, Hiroki Nakata, Yohei Saito, Kyoko Nakagawa‐Goto, Wen‐Jye Lin, Atsushi Mizokami   +21 more
wiley   +1 more source

General commentary: sexual dimorphism for juvenile body weight in lines of chickens selected for 8-week body weight. [PDF]

Front Physiol
Scanes CG.
europepmc   +1 more source

Managing Nonmetastatic Castration-resistant Prostate Cancer.

European Urology, 2019
J. Mateo, K. Fizazi, S. Gillessen, A. Heidenreich, R. Pérez-López, W. Oyen, N. Shore, Matthew R. Smith, C. Sweeney, B. Tombal, S. Tomlins, J. D. de Bono   +11 more
semanticscholar   +1 more source

Nationwide Real‐World Usage of Blood‐Based (Liquid) Biomarker Testing in Japan

Cancer Science, EarlyView.
This database analysis explores how liquid biopsy testing is integrated into clinical practice in Japan. ABSTRACT Despite the advances in precision oncology through biomarker testing, not all patients are able to benefit from treatment decisions guided by tissue‐based testing like comprehensive genomic profiling (CGP).
Yasushi Yatabe, Ryosuke Watanabe, Yuko Kotera, Shotaro Yasuoka, Daisuke Ennishi   +4 more
wiley   +1 more source

Comparison of Real-World Outcomes between Patients with BRCA1/2-Positive and Homologous Recombination Repair-Negative Metastatic Castration-Sensitive Prostate Cancer. [PDF]

Adv Ther
Bilen MA, Burbage S, Rossi C, Khilfeh I, Diaz L, Wang Y, Pilon D, Brown G, Shore N, Lowentritt B, Lin DW.   +10 more
europepmc   +1 more source

EFFECTS OF CASTRATION AND ADMINISTRATION OF METHYL TESTOSTERONE ON THE NUPTIAL COLORATION OF THE MEDAKA (ORYZIAS LATIPES) [PDF]

, 1965
Hajime Niwa
openalex   +1 more source

Fun, flirtation and fear: Selfies in teenage girls digital exchange cultures

Children &Society, EarlyView.
Abstract This paper explores teenage girls' engagement with digital images on social media. Using new feminist materialism, we foreground digital images as an assemblage of materialities (human and more‐than‐human) filled with affective potentials that materialise in/capacities.
Raksha Janak, Deevia Bhana, Valerie Reddy   +2 more
wiley   +1 more source

NASP implication in the androgen receptor associated with castration resistance in prostate cancer. [PDF]

Cell Commun Signal
Feng Y, Sun J, Kang X, Wang Y, Liu K, Wang W, Wang C, Li Y, Zhao Q, Li K, Sun FL, Chang J.   +11 more
europepmc   +1 more source

CDK12 Inactivation Attenuates Prostate Cancer Progression by Inhibiting BNIP3‐Mediated Mitophagy

Cell Proliferation, EarlyView.
In response to enzalutamide, damaged mitochondria are targeted for mitophagic degradation through the binding of BNIP3 to LC3, forming autophagosomes that are subsequently transported to lysosomes for degradation. These self‐protective mechanisms promote mitochondrial renewal, reduce oxidative stress and finally contribute to cancer cell survival ...
Mengjun Huang, Hanqi Lei, Tongyu Tong, Hailin Zou, Binyuan Yan, Fei Cao, Yiting Wang, Qiliang Teng, Bin Xu, Juan Luo, Yupeng Guan, Shaohong Lai, Peng Li, Jun Pang   +13 more
wiley   +1 more source

Synergizing Liquid Biopsy and Hybrid PET Imaging for Prognostic Assessment in Prostate Cancer: A Focus Review. [PDF]

Biomolecules
Stracuzzi F, Dall' Armellina S, Aghakhanyan G, Fanni SC, Aringhieri G, Faggioni L, Neri E, Volterrani D, Cioni D.   +8 more
europepmc   +1 more source