Results 41 to 50 of about 395,906 (262)
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T‐cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova +6 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva +8 more
wiley +1 more source
Castro Iudeorum (Puente Castro, León)
, 2015 Se presenta El Castro de los Judíos, situado a una milla de la ciudad de León o como nos precisa un documento del 13 de julio de 1197: situm super ripam de Turio iuxta Legionem, tal y como lo transcribe González (1944: 153 a 155). Se encuentra junto al barrio urbano de Puente Castro y en la horquilla conformada por el río Torío y el arroyo del Barranco,
Avello Álvarez, José Luis +1 more
openaire +1 more source
Creating space(s) for learning in prison: Developing an andragogical framework
British Educational Research Journal, EarlyView.Abstract Learning in prison is too often excluded from wider discussions of educational experiences, processes and impact. This paper proposes, for the first time, an iterative andragogical framework to conceptualise learning spaces within prison contexts.
Morwenna Bennallick +3 more
wiley +1 more source
Los castros de Zamora Occidental y Tras-os-Montes oriental : habitat y cronología
, 1983 Artículo sobre los castros de Zamora Occidental y Tras-os-Montes.
Esparza Arroyo, Ángel
core
, 2018 The density and the particularities that Iron Age hillforts show in Galicia turned them into main elements in territory organization and in social symbolism throughout the centuries.
Lixó Gómez, Carlos
core +1 more source
Prosocial behaviour in primary and secondary school students. Effects of the CYBUPRE intervention
British Educational Research Journal, EarlyView.Abstract Prosocial behaviour is regarded as a critical factor in reducing aggressive behaviours among peers, both in physical settings and virtual spaces. This variable facilitates the enhancement of social relationships, promoting empathy, deep listening, physical and verbal service, and even solidarity, among other benefits.
Mercedes Chicote‐Beato +3 more
wiley +1 more source
Análisis del patrón de asentamiento de los castros de la cuenca del Esva (Valdés-Tineo, Asturias)
, 2014 n this paper attempts to make an approach to the recognition of the settlement pattern applied to the “castros” of western Asturias, specifically in the Esva river basin, using a Geographic Information System (GIS) and statistical analysis. It also wants
García Sánchez Seco, Francisco
core
The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome
Biological Reviews, EarlyView.ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke +2 more
wiley +1 more source