Results 111 to 120 of about 1,039,561 (316)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

CAT stone print calendar

, 2008
CAT stone print ...

core  

A Systematic Literature Review of the Analysis of Costs and Other Dimensions in Process Mining and Related Disciplines

IEEE Access
Process mining allows the discovery, monitoring, and improvement of processes through records of their executions. When used for discovery, models depicting the process behavior can be obtained and then analyzed through a performance perspective ...
Ignacio Velasquez, Mario Gomez-Herrera, Marcos Sepulveda   +2 more
doaj   +1 more source

Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect

Journal of Feline Medicine and Surgery Open Reports, 2015
A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome).
Ke Shuan Chow, Niek J Beijerink, Stephen Ettinger, Reuben Fliegner, Julia A Beatty, Vanessa R Barrs   +5 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

CAT signboard at Chung

, 2008
CAT signboard at ...

core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

A revised taxonomy of the Felidae. The final report of the Cat Classification Task Force of the IUCN/SSC Cat Specialist Group

, 2017
The main task of the IUCN SSC Cat Specialist Group is the continuous review of the conservation status of all cat species and subspecies according to The IUCN Red List of Threatened Species process.
Christiansen, P., Groves, C., Tobe, S.S., Seymour, K, Sanderson, J., Christiansen, P, Hoffmann, M, Wilting, A., Gentry, A, Johnson, W E, Timmons, Zena, Seymour, K., Bruford, M W, Kitchener, A.C., Werdelin, L., O’Donoghue, P., Driscoll, C.A., Werdelin, Lars, Johnson, W.E., Duckworth, J.W., Driscoll, C A, Eizirik, E., Luo, S J, Tobe, Shanan S, Groves, Colin, Abramov, Alexei V, Meijaard, E., Bruford, M.W., Sanderson, J, Meijaard, Erik, Yamaguchi, N, Duckworth, J W, Hoffmann, M., Eizirik, E, Yamaguchi, N., Abramov, A.V., Gentry, A., Luo, S.J., Nowell, K, Kitchener, Andrew C, Wilting, Andreas, Timmons, Z., Nowell, K., Breitenmoser-Würsten, C, O’Donoghue, P, Breitenmoser-Würsten, C.   +45 more
core  

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source