Results 91 to 100 of about 2,312,470 (291)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

An Affordable AI-Driven and 3D-Printed Personalized Myoelectric Prosthesis: Design, Development, and Assessment

open access: yesIEEE Access
Upper-limb amputations significantly affect independence and quality of life, particularly in low-income regions where advanced prosthetic technology is costly and lacks adequate personalization.
Enzo Romero   +8 more
doaj   +1 more source

Counter-terrorism and national security legislation reviews: a comparative overview [PDF]

open access: yes
This paper outlines the key reviews of Australia\u27s counter-terrorism and national security legislation, followed by a more detailed comparison of the recommendations of the Independent National Security Legislation Monitor and Council of Australian ...
Cat Barker
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Anatomía quirúrgica del hígado

open access: yesOncología, 2019
Motivo de preocupación para el cirujano general ha sido abordar traumatismos y patologías hepáticas probablemente debido a la poca familiaridad con su anatomía lo cual crea inseguridad acerca de las estructuras intrahepáticas, especialmente las venas ...
Bolívar E. Villacis   +2 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Thermal Face Recognition Under Temporal Variation Conditions

open access: yesIEEE Access, 2017
In this paper, we analyze the problems produced by temporal variations of infrared face images when used in face recognition systems. The temporal variations present in thermal face images are mainly due to different environmental conditions ...
Gabriel Hermosilla Vigneau   +4 more
doaj   +1 more source

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