Results 111 to 120 of about 303,179 (311)

Genetics of inheritable diseases in cat (Felis catus)

, 2020
V diplomskem delu je predstavljeno ozadje genetskih bolezni in anomalij, ki se pojavljajo pri pasemskih ter nepasemskih mačkah. Opisani so tudi izvor domače mačke, razvoj pasem, evolucijske prilagoditve genoma, vpliv inbridinga v populacijah mačk ter ...
Jakun, Ana
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Chondroitin 4-Sulfate Disaccharide-Based Inhibitors of Cathepsin S

Polysaccharides
Cathepsin S (Cat S) is a cysteine protease involved in several human diseases (i.e., autoimmune, inflammatory and cardiovascular disorders, cancer, and psoriasis) and is an important target in drug development.
Alexis David, Roxane Domain, Florian Surback, Aude Vibert, Pierre Buisson, Martyna Maszota-Zieleniak, Ludovic Landemarre, Marie Schuler, Gilles Lalmanach, Sergey A. Samsonov, Chrystel Lopin-Bon, Fabien Lecaille   +11 more
doaj   +1 more source

Cat-associated sporotrichosis [Spanish]

Cat-associated sporotrichosis [Spanish]PARA PERSONAS QUE TIENEN CONTACTO CON GATOS: La esporotricosis asociada a los gatos es una infecci\uf3n potencialmente grave, causada por el hongo Sporothrix brasiliensis, el cual se propaga a trav\ue9s de la ...

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Toxoplasmosis not transmitted by cat bite, but high prevalence of antibodies to toxoplasma gondii in patients bitten by their own cat

, 2010
The aims of the study were to investigate the prevalence of antibodies to Toxoplasma gondii in a group of patients bitten by cats, and also to determine if toxoplasmosis can be transferred by cat bite.
Evengård, Birgitta,, Evengard, B, Westling, Katarina, Westling, K,, Jorup-Ronstrom, C, Jorup-Rönström, Christina   +5 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

The Impact of Disease on Behavior: Altering Behavior in the Course of Disease in Aging Cats

Pets
Associations between age-related diseases and behavioral alterations have been highlighted in previous studies. This study investigates the prevalence of diseases and behavioral changes in non-diseased and diseased senior cats before and after diagnosis,
Joana Eisinger, Franziska Kuhne
doaj   +1 more source

Cat-associated sporotrichosis in humans caused by Sporothrix brasiliensis [Portuguese]

Cat-associated sporotrichosis in humans caused by Sporothrix brasiliensis [Portuguese]PROFISSIONAIS DA SA aDE: a esporotricose emergente \ue9 transmitida geralmente por mordida ou arranh\ue3o de um gato infectado, e pode ter consequ\ueancias graves ...

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