Results 31 to 40 of about 303,179 (311)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Performance and overview of clinically relevant areas of application of saliva testing in the cat

open access: yesFrontiers in Veterinary Science
IntroductionThe cat represents an important model in order to investigate basic physiological knowledge of salivary secretion as well as pharmacokinetics of active substances.ObjectiveThe aim of the study was to review in which diagnostic application ...
Maike Schroers, Andrea Meyer-Lindenberg
doaj   +1 more source

Cat Flea, Ctenocephalides felis (Bouché)

open access: yesEDIS, 1997
This document provides an in-depth profile of the cat flea, Ctenocephalides felis, detailing its life cycle, distribution, and medical significance.
D.C. Zentko, D.L. Richman
doaj   +1 more source

Caregiver burden in cat owners: a cross-sectional observational study

open access: yesJournal of Feline Medicine and Surgery, 2023
Objectives Caregiver burden has been found in owners of seriously ill pets; however, research to date has been heavily represented by dog owners. Prior caregiver burden work has neither intentionally focused on cat owners nor been appropriately powered ...
Mary Beth Spitznagel   +2 more
doaj   +1 more source

Cat scratch disease

open access: yesBMJ, 2002
Unilateral lymphadenopathy of the groin is commonly seen in general practice. We report on a patient with initial features suggestive of sarcoidosis, but who, after careful history taking and further investigation, had cat scratch disease. A 29 year old woman visited her general practitioner with a painless swelling in the right groin.
Alexander, Williams   +2 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Optimization of preparation method and specificity verification of cat CD19 monoclonal antibody for disease diagnosis and treatment

open access: yesHeliyon
CD19 is a surface antigen on B cells that regulates B cell activation and proliferation, participating in B cell signaling. It is expressed in all B cell lineage tumor diseases, making CD19 a significant marker for detecting B cell tumor diseases and an ...
Liya Shen   +8 more
doaj   +1 more source

Validation of Serbian version of chronic obstructive pulmonary disease assessment test [PDF]

open access: yesVojnosanitetski Pregled, 2020
Background/Aim. The Chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is a simple and reliable tool designed to measure overall COPD related health status and complement physician assessment in routine clinical practice.
Milenković Branislava   +8 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diseases Transmitted by Cats

open access: yesMicrobiology Spectrum, 2015
ABSTRACT Humans and cats have shared a close relationship since ancient times. Millions of cats are kept as household pets, and 34% of households have cats. There are numerous diseases that may be transmitted from cats to humans.
Ellie J C, Goldstein   +1 more
openaire   +2 more sources

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