Results 71 to 80 of about 181,281 (291)
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
PLoS ONE, 2020 Tyrosine is mainly degraded in the liver by a series of enzymatic reactions. Abnormal expression of the tyrosine catabolic enzyme tyrosine aminotransferase (TAT) has been reported in patients with hepatocellular carcinoma (HCC).
Tran N Nguyen, Ha Q Nguyen, Duc-Hau Le
doaj +1 more source
Salud Pública de México, 2009 Osteoporosis is recognized worldwide as a major public health problem since many decades ago, mainly due to the cost of treatment for related fragility fractures.
Guillermo Ortiz-Luna +2 more
doaj
BCAA Catabolic Defect Alters Glucose Metabolism in Lean Mice
Frontiers in Physiology, 2019 Recent studies show branched-chain amino acid (BCAA) catabolic pathway is defective in obese animals and humans, contributing to the pathogenesis of insulin resistance and diabetes.
Ji Wang +9 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Catabolism of chylomicron triacylglycerol and cholesteryl ester in genetically obese rats
Journal of Lipid Research, 1977 The catabolism of chylomicrons was investigated in genetically obese rats and their nonobese littermates, and was compared with catabolism in older Sprague–Dawley rats with body weights similar to the obese rats and their younger controls.
T G Redgrave
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Membrane based catabolic gene array for monitoring bioremediation processes
, 2004 Bioremediation is a cost-effective method for decontamination of polluted sites. For development of effective bioremediation processes, a good understanding of the microbial processes is necessary.
Piskonen, Reetta +2 more
core +2 more sources
Characterisation of Hydrocarbon Degrading Antarctic Pseudomonas species [PDF]
, 2013 Hydrocarbon contamination of Antarctica poses a threat to the unique and fragile ecosystems of this continent. Bioremediation, utilising indigenous hydrocarbon-degrading bacteria, has been proposed as an environmentally friendly method for clean up of ...
Rhodes, Phillippa Louise
core
Advanced Healthcare Materials, EarlyView.Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma +13 more
wiley +1 more source