Results 211 to 220 of about 303,763 (330)

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, EarlyView.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

A dual L-glucose/L-galactose catabolic pathway in <i>Luteolibacter</i> species strain LG18. [PDF]

J Bacteriol
Yachida M, Shiratori Y, Iwabuchi S, Shimizu T, Nakamura A.   +4 more
europepmc   +1 more source

Apolipoprotein M attenuates age-related macular degeneration phenotypes via sphingosine-1-phosphate signaling and lysosomal lipid catabolism [PDF]

Tae Jun Lee, Andrea Santeford, Kristen Pitts, Carla Valenzuela Ripoll, Ryo Terao, Zhen Guo, Mualla Özcan, Dagmar Kratky, Christina Christoffersen, Ali Javaheri, Rajendra S. Apte   +10 more
openalex   +1 more source

Increased VLDL in nephrotic patients results from a decreased catabolism while increased LDL results from increased synthesis [PDF]

, 1998
Monique G. de Sain-van der Velden, George A. Kaysen, Hugh A. Barrett, Frans Stellaard, Mireille M. Gadellaa, Hieronymus A.M. Voorbij, Dirk‐Jan Reijngoud, Ton J. Rabelink   +7 more
openalex   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source

Precise Transcription Control Drives Optimized Catabolism of β-5-Type Lignin-Derived Dimers in <i>Sphingobium lignivorans</i> SYK-6. [PDF]

J Agric Food Chem
Kawazoe M, Kato R, Fujita M, Hishiyama S, Kamimura N, Masai E.   +5 more
europepmc   +1 more source

Alanine catabolism as a targetable vulnerability for MYC-driven liver cancer [PDF]

Tatiana Montoya, Joyce V. Lee, Longhui Qiu, Abigail S. Krall, Nedas Matulionis, Yurim Seo, Brian N. Finck, Robin Kate Kelley, Heather R. Christofk, Andrei Goga   +9 more
openalex   +1 more source

Prognostic Utility of the Preoperative Cachexia Index in Patients Undergoing Emergency Laparotomy

Annals of Gastroenterological Surgery, EarlyView.
The preoperative cachexia index, incorporating muscle mass, nutritional status, and inflammation, predicts in‐hospital and one‐year mortality in patients undergoing emergency laparotomy. This simple index may aid in risk stratification and perioperative decision‐making in high‐risk surgical patients. ABSTRACT Aim Emergency laparotomy is associated with
Naoko Fukushima, Takahiro Masuda, Kazuto Tsuboi, Masami Yuda, Keita Takahashi, Fumiaki Yano, Ken Eto   +6 more
wiley   +1 more source

Elucidation of a bacterial pathway for catabolism of the β-β-linked dilignol pinoresinol. [PDF]

mBio
Allemann MN, Lu F, Presley GN, Valentino HR, Bedgar DL, Costa MA, Moinuddin SGA, Azubuike CC, Vasileva DP, Klingeman DM, Hochanadel LH, Fisch AR, Sanders BC, Eltis LD, Giannone RJ, Davin LB, Lewis NG, Ralph J, Elkins JG, Michener JK.   +19 more
europepmc   +1 more source

The Effect of Phytohemagglutinin upon Glucose Catabolism in Lymphocytes [PDF]

, 1967
R. A. MACHAFFIE, C. H. Wang, Julia Woransberg, Jackie Spangler   +3 more
openalex   +1 more source