Results 1 to 10 of about 13,131 (127)

Catabolite repression control protein antagonist, a novel player in Pseudomonas aeruginosa carbon catabolite repression control [PDF]

Frontiers in Microbiology, 2023
In the opportunistic human pathogen Pseudomonas aeruginosa (Pae), carbon catabolite repression (CCR) orchestrates the hierarchical utilization of N and C sources, and impacts virulence, antibiotic resistance and biofilm development.
Elisabeth Sonnleitner, Flavia Bassani, Anastasia Cianciulli Sesso, Anastasia Cianciulli Sesso, Paul Brear, Branislav Lilic, Branislav Lilic, Lovro Davidovski, Armin Resch, Ben F. Luisi, Isabella Moll, Udo Bläsi   +11 more
doaj   +2 more sources

The carbohydrate utilization regulator Cbr1 coordinates nutrient-specific gene activation with selective carbon catabolite repression in a basidiomycete yeast. [PDF]

PLoS Biology
Cells must sense and respond to nutrients to survive. To efficiently grow in mixed carbon environments, microbes repress genes necessary to utilize carbon sources that require substantial resources to catabolize when a simpler carbon source, such as ...
Brandon Reyes-Chavez, Joshua D Kerkaert, Lori B Huberman   +2 more
doaj   +2 more sources

Development of an auto-inducible expression system by nitrogen sources switching based on the nitrogen catabolite repression regulation [PDF]

Microbial Cell Factories, 2022
Background The construction of protein expression systems is mainly focused on carbon catabolite repression and quorum-sensing systems. However, each of these regulatory modes has an inherent flaw, which is difficult to overcome.
Qin Yan, Laichuang Han, Xinyue Liu, Cuiping You, Shengmin Zhou, Zhemin Zhou   +5 more
doaj   +2 more sources

Removing carbon catabolite repression in Parageobacillus thermoglucosidasius DSM 2542 [PDF]

Frontiers in Microbiology, 2022
Parageobacillus thermoglucosidasius is a thermophilic bacterium of interest for lignocellulosic biomass fermentation. However, carbon catabolite repression (CCR) hinders co-utilization of pentoses and hexoses in the biomass substrate.
Jinghui Liang, Jinghui Liang, Richard van Kranenburg, Richard van Kranenburg, Albert Bolhuis, David J. Leak, David J. Leak   +6 more
doaj   +2 more sources

Preliminary study on the effect of catabolite repression gene knockout on p-nitrophenol degradation in Pseudomonas putida DLL-E4 [PDF]

PLoS ONE, 2022
P-nitrophenol (PNP) is a carcinogenic, teratogenic, and mutagenic compound that can cause serious harm to the environment. A strain of Pseudomonas putida DLL-E4, can efficiently degrade PNP in a complex process that is influenced by many factors ...
Shuang Li, Yichao Tang, Lingran Tang, Xuanyu Yan, Jiali Xiao, Huijun Xiang, Qing Wu, Ruqi Yu, Yushi Jin, Jingyu Yu, Nuo Xu, Chu Wu, Shengqin Wang, Chuanhua Wang, Qiongzhen Chen   +14 more
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When metabolic prowess is too much of a good thing: how carbon catabolite repression and metabolic versatility impede production of esterified α,ω-diols in Pseudomonas putida KT2440 [PDF]

Biotechnology for Biofuels, 2021
Background Medium-chain-length α,ω-diols (mcl-diols) are important building blocks in polymer production. Recently, microbial mcl-diol production from alkanes was achieved in E. coli (albeit at low rates) using the alkane monooxygenase system AlkBGTL and
Chunzhe Lu, Christos Batianis, Edward Ofori Akwafo, Rene H. Wijffels, Vitor A. P. Martins dos Santos, Ruud A. Weusthuis   +5 more
doaj   +2 more sources

Atmospheric hydrogen consumption is regulated by glycerol-mediated catabolite repression in mycobacteria [PDF]

mSystems
Consumption of atmospheric hydrogen (H2) enables diverse aerobic microorganisms to grow and persist in resource-deprived environments. In the aerobic saprophyte Mycobacterium smegmatis, hydrogen oxidation is catalyzed by two differentially expressed ...
Ashleigh Kropp, James D. Archer, Marion Jespersen, Thomas D. Watts, Jessica Solari, Cheng Huang, Ralf B. Schittenhelm, Rhys Grinter, Chris Greening   +8 more
doaj   +2 more sources

Modulating Chitinase in the QS Biosensor Strain CV026: Do Not Forget to Release Carbon Catabolite Repression. Comment on Deryabin et al. Quorum Sensing in Chromobacterium subtsugae ATCC 31532 (Formerly Chromobacterium violaceum ATCC 31532): Transcriptomic and Genomic Analyses. Microorganisms 2025, 13, 1021 [PDF]

Microorganisms
Chitinolytic activity is a well-documented phenotype controlled by quorum sensing (QS) in Chromobacterium strains but also regulated by carbon catabolite repression mechanisms.
Alex Leite Pereira, Fernanda Favero, Angelo Henrique Lira Machado   +2 more
doaj   +2 more sources

What are the signals that control catabolite repression in Pseudomonas? [PDF]

Microbial Biotechnology
Metabolically versatile bacteria exhibit a global regulatory response known as carbon catabolite repression (CCR), which prioritizes some carbon sources over others when all are present in sufficient amounts.
Renata Moreno, Fernando Rojo
doaj   +2 more sources

Utilization of carbon catabolite repression for efficiently biotransformation of anthraquinone O-glucuronides by Streptomyces coeruleorubidus DM [PDF]

Frontiers in Microbiology
Carbon catabolite repression (CCR) is a highly conserved mechanism that regulates carbon source utilization in Streptomyces. CCR has a negative impact on secondary metabolite fermentation, both in industrial and research settings.
Chen Tao, Quyi Wang, Junyang Ji, Ziyue Zhou, Bingjie Yue, Ran Zhang, Shu Jiang, Shu Jiang, Tianjie Yuan   +8 more
doaj   +2 more sources