Results 191 to 200 of about 185,752 (258)

Analyzing the Translatome of Lymphatic and Venous Endothelial Cells In Vivo via Translating Ribosome Affinity Purification (TRAP). [PDF]

Bio Protoc
Olayinka O, Zarinebaf L, Jung HM.
europepmc   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Repurposing clinically safe drugs for DNA repair pathway choice in CRISPR genome editing and synthetic lethality. [PDF]

Nat Commun
Macak D, Kanis P, Riesenberg S.
europepmc   +1 more source

[Catalog /

, 1907
openaire   +2 more sources

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source

SiMPull-POP: Quantification of Membrane Protein Assembly via Single Molecule Photobleaching. [PDF]

Bio Protoc
Schuck RJ, Ward AE, Barrera FN, Lamichhane R.   +3 more
europepmc   +1 more source

Sex-specific acceleration of Alzheimer's pathogenesis by chronic sleep-deprivation. [PDF]

Alzheimers Dement
Wear D, Morrone CD, Simpson D, Liu F, Hussaini SA, Yu WH.   +5 more
europepmc   +1 more source

[CATALOG]

JAPANES JOURNAL OF MEDICAL INSTRUMENTATION, 1994
openaire   +2 more sources

Caspase-8 expression in CD8⁺ T cells promotes pathogen restriction in the brain during <i>Toxoplasma gondii</i> infection. [PDF]

Sci Adv
Sibley LA, Cowan MN, Kelly AG, Amadi NA, Babcock IW, Labuzan SA, Kovacs MA, Batista SJ, Lukens JR, Harris TH.   +9 more
europepmc   +1 more source

Structural basis for childhood antibody recognition of the human metapneumovirus fusion protein. [PDF]

Nat Commun
Khalil AM, Ghazi Esfahani B, Miller RJ, Huang J, Kuan G, Balmaseda A, Gordon A, Mousa JJ.   +7 more
europepmc   +1 more source