Results 211 to 220 of about 209,821 (326)

ASO Therapy Targeting STAU2 to Inhibit Pancreatic Ductal Adenocarcinoma Progression and Metastasis by Regulating the PALLD‐Mediated EMT Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding   +16 more
wiley   +1 more source

Nanoplastics Enhance Transmembrane Transport and Uptake of Carcinogens: Transcriptional Changes and the Effects of Weathering

open access: yesAdvanced Science, EarlyView.
Nanoplastics exposed to defined weathering conditions are systematically investigated as vectors for polycyclic aromatic hydrocarbons (PAHs). This investigation demonstrates significant potential for enhancing PAH uptake and transport in an intestinal membrane model.
Erik B. Schiferle   +5 more
wiley   +1 more source

Weyl Fermion Manipulation Through Magnetic Transitions in the Ferromagnetic Non‐Centrosymmetric Weyl Semimetal PrAlSi

open access: yesAdvanced Electronic Materials, EarlyView.
During the ferromagnetic phase transition in inversion‐symmetry broken PrAlSi, both the energy/momentum positions and the number of Weyl points can be altered. These modifications induce a net chirality charge and affect the optical conductivity, positioning PrAlSi as a model system for controlling topological states through intrinsic magnetism ...
Kaipu Wang   +17 more
wiley   +1 more source

Genetically Predicted 1400 Blood Metabolites in Relation to Risk of Prostate Cancer: A Mendelian Randomization Study

open access: yesAGING MEDICINE, EarlyView.
This study employed Mendelian Randomization to assess 1,400 blood metabolites and found a significant inverse association between the glycine‐to‐serine ratio and prostate cancer risk, suggesting a potential causal relationship. ABSTRACT Objectives Metabolic dysregulation is common in cancer, yet evidence linking circulating metabolites to causal ...
Xiaojin Lu   +8 more
wiley   +1 more source

Human introns contain conserved tissue-specific cryptic poison exons. [PDF]

open access: yesNAR Genom Bioinform
Margasyuk S   +5 more
europepmc   +1 more source

Measuring specialty crop grower willingness to pay for genetic modification and genetic editing

open access: yesAgribusiness, EarlyView.
Abstract In contrast to the widespread adoption of agricultural commodities modified using biotechnology, the adoption rate of bioengineered specialty crops by growers remains low. The use of bioengineered crops has been controversial since their introduction in the 1990s due to concerns about their potentially harmful effects to human health, the ...
Marie Abbey   +5 more
wiley   +1 more source

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