Results 261 to 270 of about 196,002 (296)

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

open access: yesAdvanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li   +4 more
wiley   +1 more source

Lignocellulose-mediated selection of halophilic PET-degrading enzymes from mangrove soil

open access: yes
Peña-Valencia M   +12 more
europepmc   +1 more source

Topological Approach to Void Finding Applied to the SDSS Galaxy Map. [PDF]

open access: yesAstrophys J
Aggarwal M   +4 more
europepmc   +1 more source

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li   +19 more
wiley   +1 more source

Smart Microbiomes: How AI Is Revolutionizing Personalized Medicine. [PDF]

open access: yesBioengineering (Basel)
Alexandrescu L   +13 more
europepmc   +1 more source

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