Results 81 to 90 of about 184,861 (296)

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Library catalogs in the Web 2.0 environment

Cybrarians Journal, 2011
The study discusses the recent developments that have occurred or are expected to occur in library catalogs in the Web 2.0 environment, which include supporting beneficiary participation in content, which is one of the most important characteristics of ...
Mahmoud Khalifa
doaj   +1 more source

SPITZER POINT-SOURCE CATALOGS OF ~ 300,000 STARS IN SEVEN NEARBY GALAXIES [PDF]

, 2015
We present Spitzer IRAC 3.6–8 &mgr; m ?> and Multiband Imaging Photometer 24 &mgr; m ?> point-source catalogs for seven galaxies: NGC 6822, M33, NGC 300, NGC 2403, M81, NGC 0247, and NGC 7793.
Rubab Khan, Rubab Khan, K. Stanek, C. Kochanek, G. Sonneborn   +4 more
semanticscholar   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

EXOPLANET POPULATION INFERENCE AND THE ABUNDANCE OF EARTH ANALOGS FROM NOISY, INCOMPLETE CATALOGS [PDF]

, 2014
No true extrasolar Earth analog is known. Hundreds of planets have been found around Sun-like stars that are either Earth-sized but on shorter periods, or else on year-long orbits but somewhat larger.
D. Foreman-Mackey, D. Hogg, T. Morton
semanticscholar   +1 more source

Assessing the Ecological Value: Monetizing Process Innovations in Tailored Forming

Advanced Engineering Materials, EarlyView.
This article introduces a method for evaluating the sustainability of innovations, even with limited data. The method is illustrated through an analysis of the “Tailored Forming” technology, which explores the impact of sustainability on economic value added.
Jonas Schneider, Jan Westing, Matthias Schmidt, Peter Nyhuis, Vivian Katharina Kuprat   +4 more
wiley   +1 more source

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

CANDELS MULTI-WAVELENGTH CATALOGS: SOURCE DETECTION AND PHOTOMETRY IN THE GOODS-SOUTH FIELD [PDF]

, 2013
We present a UV to mid-infrared multi-wavelength catalog in the CANDELS/GOODS-S field, combining the newly obtained CANDELS HST/WFC3 F105W, F125W, and F160W data with existing public data.
Yicheng Guo, Yicheng Guo, H. Ferguson, M. Giavalisco, G. Barro, S. Willner, M. Ashby, T. Dahlén, J. Donley, S. Faber, A. Fontana, A. Galametz, A. Grazian, Kuang-Han Huang, Kuang-Han Huang, D. Kocevski, A. Koekemoer, D. Koo, E. McGrath, M. Peth, M. Salvato, S. Wuyts, M. Castellano, A. Cooray, M. Dickinson, J. Dunlop, G. Fazio, J. Gardner, E. Gawiser, N. Grogin, N. Hathi, L. Hsu, Kyoung-soo Lee, R. Lucas, B. Mobasher, K. Nandra, J. Newman, A. V. D. Wel   +37 more
semanticscholar   +1 more source

A Universal Biomimetic Approach for Making Artificial Antigen‐Presenting Cells for T Cell Activation

Advanced Functional Materials, EarlyView.
This study shows a biomimetic silica microcapsule (SMC) fabrication method under mild conditions for making artificial antigen‐presenting cells (aAPCs). Inspired by marine biomineralization, peptide‐mediated biosilicification enables silica shell formation on emulsion templates. The resulting SMCs possess a core–shell structure, controlled fluorescence
Fei Hou, Supun Ranaweera, Xiangke Li, Ruirui Qiao, Yue Hui, Chun‐Xia Zhao   +5 more
wiley   +1 more source