Results 111 to 120 of about 3,048 (284)

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

open access: yesAdvanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang   +7 more
wiley   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Flipping the cataloguing class: equipping and empowering cataloguers for the hybrid cataloguing environment [PDF]

open access: yes, 2014
With not only the Library of Congress and British Library moving to RDA in 2013 (Wiggins, 2012; Danskin, 2013), but also major research libraries including Cambridge University Library, the Bodleian and Trinity College, Dublin (Carty, 2013; O’Reilly ...
Welsh, A
core  

DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics

open access: yesAdvanced Science, EarlyView.
This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei   +12 more
wiley   +1 more source

MARC zapisi i XML = Marc records and XML [PDF]

open access: yes, 2004
This article describes how a MARC record has evolved in the decades since its introduction, i.e. from the ISO 2709 to XML format. The XML format is a general format for presenting MARC records in a simple and understandable way.
Budimir, Gordana
core  

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

open access: yesAdvanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang   +3 more
wiley   +1 more source

Open Access to Cataloguing Rules [PDF]

open access: yes, 2012
The possibility for librarians and developers to have access to cataloguing rules is not a minor issue. There are many open access movements all over the world, and involving all kinds of contents, not only research and data, but also standards ...
Bertolini, María Violeta
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

What constitutes cataloguing quality? a review of issues and perceptions

open access: yes, 2018
Adherence to the quality in cataloguing has been the concern of catalogues for decades. This paper reviews various perceptions on issues related to cataloguing quality, which in reality vary among cataloguers. Cataloguing standards acts as guidelines for
Harinarayana, N. S., Chandrappa
core  

Home - About - Disclaimer - Privacy