Results 161 to 170 of about 55,736 (295)
Towards a FAIR metadata framework for drone and uncrewed aerial vehicle data. [PDF]
Ellsäßer FJ, Nikuze A.
europepmc +1 more source
Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang +14 more
wiley +1 more source
A systems level framework for postharvest physiology and quality preservation. [PDF]
García-Pastor ME, Falagán N.
europepmc +1 more source
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
Les normes internacionals de catalogació a Catalunya
Anglada i de Ferrer, Lluís M.
doaj +1 more source
Proteoform medicine: characterizing and targeting protein forms in human disease. [PDF]
Korchak JA +4 more
europepmc +1 more source
Governance and Cooperation Aspects: the Case of PICA from a Librarian's Point of View [PDF]
Klugkist, A.C.,
core +1 more source
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo +8 more
wiley +1 more source
Nummi Digitali: A pioneering multimodal platform for numismatic heritage. [PDF]
Sole L +7 more
europepmc +1 more source

