SAT1‐Induced Spermidine Depletion Potentiates Food Allergy
Spermidine depletion, driven by upregulated spermidine/spermine N1‐acetyltransferase (SAT1), potentiates food allergy by promoting mast cell degranulation through autophagy suppression. SAT1 physically interacts with the long noncoding RNA Cdk19os to inhibit Atg5 and Atg7, disrupting autophagic flux.
Manman Liu +8 more
wiley +1 more source
The 'Lifeboat Hypothesis': Aquatic Microplastics in a Warming World-Climate-Resilient Refugia for Bacterial Pathogens. [PDF]
Quilliam RS, Ormsby MJ.
europepmc +1 more source
Dual Repression by IPA1 Fine‐Tunes OsbZIP79‐Mediated Salt Tolerance in Rice
Dual repression by IPA1 fine‐tunes OsbZIP79‐mediated salt tolerance in rice: direct transcriptional inhibition under normal conditions and salt‐induced degradation under stress. This dual mechanism activates OsbZIP79 to regulate Na+/K+ homeostasis and redox balance via downstream genes, enabling optimal salt stress response.
Hui Wang +12 more
wiley +1 more source
From Cabinet to Catalogue: The Palaearctic bee (Hymenoptera, Apoidea, Anthophila) collection of the Museu Nacional de História Natural e da Ciência, Universidade de Lisboa, Portugal. [PDF]
Baptista M, de Sousa P, Keller RA.
europepmc +1 more source
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi +16 more
wiley +1 more source
Las normas internacionales de catalogación en Cataluña
Anglada i de Ferrer, Lluís M.
doaj
Transcribing historical Canadian weather data. [PDF]
Slonosky V +4 more
europepmc +1 more source
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Multimodal Assessment of Biomechanical and Neuromuscular Characteristics of Zygomaticus Major in Healthy Participants. [PDF]
Garg R +6 more
europepmc +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source

