Results 41 to 50 of about 1,670,157 (352)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Efficient catalytic removal of COS and H2S over graphitized 2D micro-meso-macroporous carbons endowed with ample nitrogen sites synthesized via mechanochemical carbonization

Green Energy & Environment, 2022
Developing a suitable catalyst for the elimination of highly toxic carbonyl sulfide (COS) and hydrogen sulfide (H2S) is of great significance in terms of industrial safety and environmental protection.
Xun Kan, Guanqing Zhang, Yingying Luo, Fujian Liu, Yong Zheng, Yihong Xiao, Yanning Cao, Chak-tong Au, Shijing Liang, Lilong Jiang   +9 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Alkaline-Earth Metals-Doped Pyrochlore Gd2Zr2O7 as Oxygen Conductors for Improved NO2 Sensing Performance

Scientific Reports, 2017
This work proposed a novel strategy to fabricate highly-stable NO2 sensor based on a pyrochlore-phase Gd2Zr2O7 oxygen conductor. The incorporation of alkaline-earth metals distinctly enhances the sensing performance of the Gd2Zr2O7 based sensors.
Fulan Zhong, Jiwu Zhao, Lanqian Shi, Yihong Xiao, Guohui Cai, Yong Zheng, Jinlin Long   +6 more
doaj   +1 more source

Nitrogen- and Halogen-Free Multifunctional Polymer-Directed Fabrication of Aluminum-Rich Hierarchical MFI Zeolites

Nanomaterials, 2022
Aluminum-rich hierarchical MFI-type zeolites with high acidic-site density exhibit excellent activity and selectivity in bulky molecule-involved reactions.
Yuan Hu, Chan Wang, Tiesen Li, Xiaojun Bao, Yuanyuan Yue   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Dynamic oxygen adsorption on single-atomic Ruthenium catalyst with high performance for acidic oxygen evolution reaction

Nature Communications, 2019
Achieving active and stable oxygen evolution reaction (OER) in acid media based on single-atom catalysts is highly promising for cost-effective and sustainable energy supply in proton electrolyte membrane electrolyzers.
Linlin Cao, Q. Luo, Jiajia Chen, Lan Wang, Yue Lin, Huijuan Wang, Xiaokang Liu, Xinyi Shen, Wei Zhang, Wei Liu, Z. Qi, Zheng Jiang, Jinlong Yang, T. Yao   +13 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source