Results 261 to 270 of about 850,147 (309)

Mechanism-Based Catalytic Antibody Inactivation

Biochemical and Biophysical Research Communications, 1993
Studies of alternative substrates of the catalytic monoclonal antibodies 18H4, 7D4, and 45A11 provided us with a better understanding of the mechanism of ester hydrolysis employed by these isoabzymes. The antibodies were studied with analogs of the substrate, phenyl acetate; N-acetylglycine phenyl ester 3 and N-carbobenzoxy-glycine phenyl ester 4.
T S, Angeles, M T, Martin
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Catalytic reactions—I Mechanisms

Talanta, 1970
The mechanisms of some reactions used in catalytic analysis are discussed. The knowledge of the mechanism of a catalytic reaction can help in the development of new catalytic reactions and the choice of optimal conditions, and to show the possibilities for further increases in sensitivity.
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Catalytic Mechanism of Cdc25

Biochemistry, 2002
Cdc25 is a dual-specificity phosphatase that catalyzes the activation of the cyclin-dependent kinases, thus causing initiation and progression of successive phases of the cell cycle. Although it is not significantly homologous in sequence or structure to other dual-specificity phosphatases, Cdc25 belongs to the class of well-studied cysteine ...
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Catalytic mechanism of tyrosinases

Tyrosinases (TYR) play a key role in melanin biosynthesis by catalyzing two reactions: monophenolase and diphenolase activities. Despite low amino acid sequence homology, TYRs from various organisms (from bacteria to humans) have similar active site architectures and catalytic mechanisms. The active site of the TYRs contains two copper ions coordinated
Samaneh, Zolghadri, Ali Akbar, Saboury
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Catalytic Reaction Mechanism Testing

Russian Journal of Physical Chemistry B, 2008
Experimental tests for determining the mechanism of catalytic reactions were suggested. Quantitative relations were obtained that allowed the mechanism of formation of product molecules in an arbitrary catalytic reaction to be determined by isothermic relaxation methods.
V. F. Kharlamov, F. V. Kharlamov
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Catalytic RNA: Structure and Mechanism

Biochemical Society Transactions, 1993
The Hopkins Lecturer is given the charge of explaining how advances in other fields of science have had an impact on his or her own field of biochemistry. A moment’s thought revealed that it was not at all difficult to think of examples where other scientific fields have provided necessary groundwork for the study of RNA catalysis or RNA biochemistry ...
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Enzymes and Catalytic Mechanisms

2007
Enzymes catalyze the biochemical reactions in cells of all organisms. These reactions constitute the chemical basis of life. Most enzymes are proteins—a few are ribonucleic acids or ribonucleoproteins—and the catalytic machinery is located in a relatively small active site, where substrates bind and are chemically processed into products. Illustrations
Perry A. Frey, Adrian D. Hegeman
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Aldehyde Dehydrogenase Catalytic Mechanism

1999
Elsewhere in this volume we detail findings from an alignment of 145 ALDH sequences (Perozich et al., 1999), and previously at these meetings we reported that the crystal structure of a class 3 ALDH (E-NAD binary complex) revealed a non-traditional mode of NAD-binding within an open β/α domain otherwise familiar in the NAD-binding “ossmann folds” of ...
John Hempel, John Perozich, Toby Chapman, John Rose, Josette S. Boesch, Zhi-Jie Liu, Ronald Lindahl, Bi-Cheng Wang   +7 more
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Catalytic mechanism of UDP-glucose dehydrogenase

Biochemical Society Transactions, 2019
Abstract UDP-glucose dehydrogenase (UGDH), an oxidoreductase, catalyzes the NAD+-dependent four-electron oxidation of UDP-glucose to UDP-glucuronic acid. The catalytic mechanism of UGDH remains controversial despite extensive investigation and is classified into two types according to whether an aldehyde intermediate is generated in the ...
Jun Chen, Shulin Yang
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The Catalytic Mechanism of Peroxiredoxins

2007
Peroxiredoxins carry out the efficient reduction of a typically broad range of peroxide substrates through an absolutely conserved, activated cysteine residue within a highly conserved active site pocket structure. Though details of reductive recycling after cysteine sulfenic acid formation at the active site vary among members of different Prx classes,
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