Results 61 to 70 of about 152,478 (263)

Nanozymes in Reactive Oxygen Species‐Dependent Diseases: From Design and Preclinical Studies to Clinical Translation Prospects

open access: yesSmall Structures, EarlyView.
Nanozymes emerge as promising therapeutic agents for reactive oxygen species (ROS)‐dependent diseases, offering advantages over traditional biocatalysts through enhanced stability, tunability, and targeting capabilities. This review explores their mechanisms, design strategies, and clinical progress, emphasizing precision medicine potential.
Lihong Zhou   +8 more
wiley   +1 more source

An Interpretable Artificial Intelligence System for Crohn's Disease Ulcer Identification and Grading on Double‐Balloon Enteroscopy Images

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background Crohn's disease (CD) is an incurable inflammatory bowel disease that can lead to a variety of complications and requires lifelong treatment. However, the diagnosis and management of Crohn's disease exhibit high rates of misdiagnosis and missed diagnoses, along with significant variability, among primary care facilities and novice ...
Qiuyuan Liu   +16 more
wiley   +1 more source

Performance of international phenotypic criteria for prenatal exome sequencing: systematic review and comparative diagnostic accuracy study using historical individual participant data

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To evaluate: (i) the performance of the National Health Service (NHS) phenotypic eligibility criteria for prenatal exome sequencing (pES); (ii) the diagnostic yield of individual NHS criteria; (iii) the diagnostic yield when one or multiple NHS criteria were met; and (iv) the performance of the NHS criteria compared with that of ...
K. Reilly   +23 more
wiley   +1 more source

Sauteur d'Alfort rabbit‐like locomotory disturbances and eye disorders in two pet rabbits—‘handstand rabbits’

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract Homozygous sauteur d'Alfort rabbits have a splicing‐site mutation in the RAR‐related orphan receptor B (RORB) gene that causes changes in their locomotion. These rabbits sometimes walk on their thoracic limbs, especially at higher speeds. They also experience additional abnormalities, including eye alterations such as blindness due to retinal ...
Kerstin Müller   +4 more
wiley   +1 more source

Equine fasciolosis due to Fasciola hepatica in the Community of Madrid (Spain): First report of a rare parasitic infection in horses

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract We reported for the first time a confirmed case of equine fasciolosis in the Community of Madrid (Spain). Here, we described the clinical presentation, diagnostic approach and treatment of the affected horse, as well as the seroprevalence of Fasciola hepatica in the equestrian centre where it was detected.
Carolina R. Sanz   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy