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Current Trends in the Pharmacotherapy of Cataracts

open access: yesPharmaceuticals, 2020
Cataracts, one of the leading causes of preventable blindness worldwide, refers to lens degradation that is characterized by clouding, with consequent blurry vision.
Segewkal Hawaze Heruye   +2 more
exaly   +3 more sources

Cataract [PDF]

open access: yesNature Reviews Disease Primers, 2015
Cataract is the leading cause of reversible blindness and visual impairment globally. Blindness from cataract is more common in populations with low socioeconomic status and in developing countries than in developed countries. The only treatment for cataract is surgery.
Lam, Dennis   +9 more
openaire   +5 more sources

High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology

open access: yesCells, 2023
Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to characterize the genes linked to this developmental defect and to define their downstream ...
Archana D. Siddam   +8 more
doaj   +1 more source

Cataract and surgery for cataract [PDF]

open access: yesBMJ, 2006
Cataract surgery is the commonest single surgical procedure carried out in the developed world. In the developing world, cataract remains the commonest cause of blindness. In 1990 an estimated 37 million people were blind worldwide—40% of them because of cataract.1 Every year, an extra 1-2 million people go blind.
David, Allen, Abhay, Vasavada
openaire   +2 more sources

Autophagy in the eye: from physiology to pathophysiology

open access: yesAutophagy Reports, 2023
Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy is emerging as a
Paloma B. Liton   +15 more
doaj   +1 more source

Pharmacologic pupillary constriction after dilated fundus examination for ectopia lentis to prevent further subluxation

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: To describe two cases of ectopia lentis with different preoperative management strategies following the initial diagnostic dilated exam. Observations: In both cases, the patients presented with bilateral subluxation of the crystalline lens ...
William Plum   +5 more
doaj   +1 more source

Evaluation of the Influence of Clinical History on the Occurrence of Dementia Using the Database of National Health Insurance in Japan

open access: yesJournal of Ageing and Longevity, 2023
The global incidence of dementia has been rising for the past several years, posing significant health challenges regarding its management and prevention. Dementia is associated with a substantial burden on patients and their families.
Yoh Tamaki   +2 more
doaj   +1 more source

Zinc and Copper Ions Induce Aggregation of Human β-Crystallins

open access: yesMolecules, 2022
Cataracts are defined as the clouding of the lens due to the formation of insoluble protein aggregates. Metal ions exposure has been recognized as a risk factor in the cataract formation process. The γ and β crystallins are members of a larger family and
Vanesa Ramirez-Bello   +3 more
doaj   +1 more source

The Evolving Role of Ophthalmology Clinics in Screening for Early Alzheimer’s Disease: A Review

open access: yesVision, 2020
Alzheimer’s disease (AD) is the leading cause of dementia, which is a growing public health concern. Although there is no curative treatment for established AD, early recognition and modification of the known risk factors can reduce both severity and the
Paris Dickens, Kanna Ramaesh
doaj   +1 more source

Cataracts are Associated with the Coexistence of Moderate to Severe Obstructive Sleep Apnea and Diabetes Mellitus [PDF]

open access: yesSleep Medicine Research, 2020
Background and Objective The individual presence of diabetes mellitus (DM) or obstructive sleep apnea (OSA) is significantly associated with cataract formation, but few studies have examined the association of cataracts with comorbid DM and OSA.
Seungku Lee   +4 more
doaj   +1 more source

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