Results 171 to 180 of about 59,243 (340)

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami   +6 more
wiley   +1 more source

The physiological response of juvenile diploid and triploid Arctic charr Salvelinus alpinus to exhaustive exercise

open access: yesJournal of Fish Biology, EarlyView.
Abstract Triploidy is an effective tool for producing sterile fishes but often results in impaired performance in commercial aquaculture. In light of this, our study compared the physiological response to exhaustive exercise in juvenile diploid and triploid Arctic charr Salvelinus alpinus, a polar species with great potential for aquaculture.
John D. Clark, Tillmann J. Benfey
wiley   +1 more source

Association Between Cataract Extraction and Development of Dementia.

open access: yesJAMA Intern Med, 2022
Lee CS   +10 more
europepmc   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

open access: yesJournal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann   +8 more
wiley   +1 more source

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