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Catastrophic antiphospholipid antibody syndrome
Pediatric Nephrology, 2005Antiphospholipid antibody syndrome (APS) is characterized by recurrent thrombosis with the presence of circulating antiphospholipid antibodies. A diagnosis of APS requires the presence of at least one clinical and one laboratory criteria (detection of aCL IgG or IgM antibodies or the presence of lupus anticoagulant on two or more consecutive occasions ...
Jyoti, Sharma +5 more
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Case 294: Catastrophic Antiphospholipid Syndrome
Radiology, 2021History A 50-year-old woman presented to the emergency department of our hospital with a 2-day history of lower limb pain associated with unusual asthenia and diffuse arthralgia over the past 3 weeks. She was a native of Guinea and had lived in France for most of her life, working as a personal care assistant.
Marianne Golse +3 more
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Susac’s syndrome or catastrophic antiphospholipid syndrome?
Lupus, 2004Susac’s syndrome is a microangiopathic disorder of unknown pathogenesis presenting with encephalopathy, hearing loss and branch retinal artery occlusions. The term ‘catastrophic’ antiphospholipid syndrome (APS) is used to define a subset of the APS characterized by thrombotic microangiopathy with clinical evidence of three or more organ involvement ...
S, Bucciarelli +4 more
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Pregnancy and Catastrophic Antiphospholipid Syndrome
Clinical Reviews in Allergy & Immunology, 2008Antiphospholipid syndrome (APS) is clearly related to maternal morbidity. The most characteristic feature is pregnancy loss; however, several other serious complications had been reported including fetal growth restriction, uteroplacental insufficiency, fetal distress, pre-eclampsia, and HELLP syndrome.
Jose A, Gómez-Puerta +2 more
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Catastrophic antiphospholipid syndrome: an update
Panminerva Medica, 2017Catastrophic antiphospholipid syndrome (CAPS) is a rare variant that accounts for 1% of patients with APS. Despite its low frequency, the mortality-related is very high ranging from 50% of patients in the first series to 37% in the most recent data.
Gerard, Espinosa +2 more
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Catastrophic antiphospholipid syndrome: therapeutic developments
Expert Review of Clinical Immunology, 2007The catastrophic antiphospholipid syndrome is a potentially life-threatening condition with a high mortality rate, the diagnosis of which requires a high degree of clinical awareness on the part of attending physicians. Patients with this syndrome have various symptoms in common: clinical evidence of multiple organ involvement developed over a very ...
Ricard, Cervera, Ronald A, Asherson
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Catastrophic antiphospholipid syndrome in cancer
Haematologia, 2000Antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies resulting in arterial and venous thromboembolism. Apart from primary cases, this syndrome is often associated with autoimmune diseases. Around 50 cases of catastrophic antiphospholipid antibody syndrome have been reported as yet. Authors describe the first case of
P, Soltész +7 more
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The catastrophic antiphospholipid (Asherson's) syndrome
Autoimmunity Reviews, 2006The catastrophic antiphospholipid syndrome (CAPS, Asherson's syndrome) develops rapidly following an identifiable triggering factor (eg infection, trauma, inadequate coagulation neoplasia, obstetric) in antiphospholipid antibody positive patients. It is most frequently encountered in patients with a primary antiphospholipid syndrome or systemic lupus ...
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Catastrophic antiphospholipid syndrome and pregnancy
Seminars in Perinatology, 2018Catastrophic antiphospholipid syndrome (CAPS) is a rare but life-threatening condition that may be precipitated by pregnancy. The condition can be hard to diagnose since it mimics other thrombotic microangiopathies that are associated with pregnancy. Accurate and timely diagnosis is critical for effective treatment.
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Catastrophic Antiphospholipid Syndrome
Clinics in Laboratory Medicine, 2013Ricard Cervera +2 more
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