In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
BACKGROUND AND OBJECTIVES: Extensive literature has shown that poor sleep quality, anxiety symptoms and catastrophizing contribute to worsening of temporomandibular disorder (TMD) conditions.
Claudia Aparecida de Oliveira Machado +3 more
doaj +1 more source
Main symptoms associated to the catastrophizing in women with fibromyalgia and migraine
Objective To evaluate the main symptoms associated catastrophizing in women with fibromyalgia and migraine. Methodology We conducted an observational study with 26 women diagnosed with both fibromyalgia and migraine, aged between 30 and 60 years (46±8 ...
Amanda de Oliveira Freire Barros +5 more
doaj +1 more source
Positive Affect Is Associated With Better Physical Function in Early Rheumatoid Arthritis
Objective This study examined the association between positive affect and physical function in individuals with early rheumatoid arthritis (RA). Methods We analyzed baseline data from 129 adults with early RA (persistent joint symptoms for ≤24 months) and active disease enrolled in the Central Pain in RA 2 (CPIRA‐2) study.
Burcu Aydemir +9 more
wiley +1 more source
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil +2 more
wiley +1 more source
International Society for the Study of Women's Sexual Health (ISSWSH) review of epidemiology and pathophysiology, and a consensus nomenclature and process of care for the management of persistent genital arousal disorder/genito-pelvic dysesthesia (PGAD/GPD) [PDF]
Background Persistent genital arousal disorder (PGAD), a condition of unwanted, unremitting sensations of genital arousal, is associated with a significant, negative psychosocial impact that may include emotional lability, catastrophization, and ...
Kim, Choll W. +36 more
core +1 more source
MRI Catastrophization in Spinal Disorders: Balancing Accurate Reporting With Clinical Relevance
Rishi Mugesh Kanna +1 more
exaly +2 more sources
Psychological factors associated with pain and function in adults with hallux valgus
Introduction Psychological factors are linked to pain and function in various musculoskeletal conditions, but their impact on hallux valgus is unclear. Health‐related quality of life declines with increasing severity of hallux valgus, affecting not only ...
Abdel Kak +9 more
doaj +1 more source
What does pain sensitivity really predict in rheumatoid arthritis patients?
Objectives: The present study aimed to compare the pressure–pain threshold (PPT) values in patients with rheumatoid arthritis (RA) and age-gender matched controls with chronic nonspecific low back pain and to determine whether PPT values could be ...
Aysegül Altun Güvenir +3 more
doaj +1 more source
Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang +6 more
wiley +1 more source

