Results 1 to 10 of about 6,129,726 (293)

Central sensitization in women with endometriosis: a cross-sectional study [PDF]

BMC Women's Health
Background Pain is the primary symptom of endometriosis and may progress into a chronic, acyclic condition driven by neuroinflammatory mechanisms, leading to neuropathic and ultimately nociplastic pain.
Anna Biasioli, Francesca Previtera, Ilaria Mazzera, Matilde Degano, Silvia Zermano, Veronica Tius, Ilaria Piacenti, Renato Seracchioli, Diego Raimondo, Monica Della Martina, Martina Arcieri, Stefano Restaino, Lorenza Driul, Giuseppe Vizzielli   +13 more
doaj   +2 more sources

Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes

Frontiers in Reproductive Health, 2021
Endometriosis-associated pain and the mechanisms responsible for its initiation and persistence are complex and difficult to treat. Endometriosis-associated pain is experienced as dysmenorrhea, cyclical pain related to organ function including dysuria ...
Helen C. McNamara, Helena C. Frawley, Helena C. Frawley, Helena C. Frawley, Jacqueline F. Donoghue, Jacqueline F. Donoghue, Emma Readman, Emma Readman, Martin Healey, Martin Healey, Lenore Ellett, Lenore Ellett, Charlotte Reddington, Charlotte Reddington, Charlotte Reddington, Lauren J. Hicks, Keryn Harlow, Peter A. W. Rogers, Peter A. W. Rogers, Claudia Cheng, Claudia Cheng   +20 more
doaj   +3 more sources

Suffering from chronic tinnitus, chronic neck pain, or both: Does it impact the presence of signs and symptoms of central sensitization?

PLoS ONE, 2023
Chronic subjective tinnitus is a prevalent symptom, which has many similarities with chronic pain. Central sensitization is considered as a possible underlying mechanism of both symptoms.
Kayleigh De Meulemeester, Mira Meeus, Robby De Pauw, Barbara Cagnie, Hannah Keppler, Dorine Lenoir   +5 more
doaj   +2 more sources

Impact of central sensitization on pain intensity, pain-related symptoms, and health-related quality of life in chronic pain outpatient department

Indian Journal of Pain, 2021
Context: Central sensitization (CS) has been proposed as a common underlying pathophysiology to explain poorly understood pain-related syndromes. This is termed under central sensitivity syndromes (CSSs), for which no specific organic cause has been ...
Deep Divanshu Lall, Rajat Gupta, Nandini Dadu, Ashu Jain   +3 more
doaj   +1 more source

Negative correlation between central sensitization and forgotten joint score-12 after total hip arthroplasty

Journal of Orthopaedic Surgery and Research, 2023
Background Central sensitization is a condition in which even mild stimuli cause pain due to increased neuronal reactivity in the dorsal horn of the spinal cord. It is one of factors of chronic pain in patients with osteoarthritis. However, it is unknown
Takashi Imagama, Tomoya Okazaki, Yuta Matsuki, Takehiro Kaneoka, Takehiro Kawakami, Kazuhiro Yamazaki, Takashi Sakai   +6 more
doaj   +1 more source

Estrogen Mediates the Sexual Dimorphism of GT1b-Induced Central Pain Sensitization

Cells, 2023
We have previously reported that the intrathecal (i.t.) administration of GT1b, a ganglioside, induces spinal cord microglia activation and central pain sensitization as an endogenous agonist of Toll-like receptor 2 on microglia.
Jaesung Lee, Seohyun Chung, Minkyu Hwang, Yeongkag Kwon, Seung Hyun Han, Sung Joong Lee   +5 more
doaj   +1 more source

Effect of central sensitization on dizziness-related symptoms of persistent postural-perceptual dizziness

BioPsychoSocial Medicine, 2022
Background Persistent postural-perceptual dizziness (PPPD) is a chronic functional dizziness symptom triggered by psychological stress, but its pathophysiology is unknown.
Kazuaki Hashimoto, Takeaki Takeuchi, Takayuki Ueno, Shunsuke Suka, Miki Hiiragi, Maya Yamada, Akiko Koyama, Yuzo Nakamura, Jun Miyakoda, Masahiro Hashizume   +9 more
doaj   +1 more source

Association of central sensitization, visceral fat, and surgical outcomes in lumbar spinal stenosis

Journal of Orthopaedic Surgery and Research, 2023
Background Controversy remains regarding predictors of surgical outcomes for patients with lumbar spinal stenosis (LSS). Pain sensitization may be an underlying mechanism contributing to LSS surgical outcomes.
Izaya Ogon, Hiroyuki Takashima, Tomonori Morita, Ryunosuke Fukushi, Tsuneo Takebayashi, Atsushi Teramoto   +5 more
doaj   +1 more source

Cultural Validation of the Chinese Central Sensitization Inventory in Patients with Chronic Pain and its Predictive Ability of Comorbid Central Sensitivity Syndromes

Journal of Pain Research, 2022
Beibei Feng,1,2 Xiaoqian Hu,3 William Weijia Lu,2 Yuling Wang,1 Wing Yuk Ip2 1Rehabilitation Medicine Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510655, People’s Republic of China; 2Department of Orthopaedics ...
Feng B, Hu X, Lu WW, Wang YL, Ip WY
doaj  

Central sensitization and adult attention deficit hyperactivity disorder in medical students with chronic back pain: a cross-sectional study

Egyptian Rheumatology and Rehabilitation, 2022
Background Chronic back pain is a common health complaint among university students. A subset of chronic back pain patients suffer from increased pain sensitivity, a process termed central sensitization.
Maha E. Ibrahim, Mohamed A. Hefny
doaj   +1 more source