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Peripheral and central sensitization [PDF]

open access: yesRevista Dor, 2016
BACKGROUND AND OBJECTIVES: Central sensitization is an important phenomenon for pain chronicity and is present in neuropathic pain. This study aimed at addressing some pathophysiological aspects of this phenomenon. CONTENTS: Some extra and intracellular
Hazem Adel Ashmawi   +1 more
doaj   +3 more sources

Itch: from the skin to the brain – peripheral and central neural sensitization in chronic itch

open access: yesFrontiers in Molecular Neuroscience, 2023
Similar to chronic pain, chronic itch is frequently linked to neural sensitization, a phenomenon wherein the nervous system becomes hypersensitive to stimuli.
Omar Mahmoud   +3 more
doaj   +3 more sources

Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes

open access: yesFrontiers in Reproductive Health, 2021
Endometriosis-associated pain and the mechanisms responsible for its initiation and persistence are complex and difficult to treat. Endometriosis-associated pain is experienced as dysmenorrhea, cyclical pain related to organ function including dysuria ...
Helen C. McNamara   +20 more
doaj   +3 more sources

Peripheral itch sensitization in atopic dermatitis

open access: yesAllergology International, 2022
Atopic dermatitis is a skin disorder caused by skin dryness and barrier dysfunction, resulting in skin inflammation and chronic itch (or pruritus). The pathogenesis of atopic dermatitis is thought to be initiated by a lowering of the itch threshold due ...
Mitsutoshi Tominaga, Kenji Takamori
doaj   +3 more sources

Potential Neuroimmune Interaction in Chronic Pain: A Review on Immune Cells in Peripheral and Central Sensitization

open access: yesFrontiers in Pain Research, 2022
Chronic pain is a long-standing unpleasant sensory and emotional feeling that has a tremendous impact on the physiological functions of the body, manifesting itself as a dysfunction of the nervous system, which can occur with peripheral and central ...
Jia-Xuan Yang   +11 more
doaj   +3 more sources

Wallet Neuritis – An Example of Peripheral Sensitization [PDF]

open access: yesCurrent Rheumatology Reviews, 2018
Wallet neuritis is an example of extra-spinal tunnel neuropathy concerning sciatic nerve. Its clinical appearance often gets confused with sciatica of lumbar spine origin. Wallet- induced chronic sciatic nerve constriction produces gluteal and ipsilateral lower extremity pain, tingling, and burning sensation.

exaly   +3 more sources

The dual role of TRPV1 in peripheral neuropathic pain: pain switches caused by its sensitization or desensitization

open access: yesFrontiers in Molecular Neuroscience
The transient receptor potential vanilloid 1 (TRPV1) channel plays a dual role in peripheral neuropathic pain (NeuP) by acting as a “pain switch” through its sensitization and desensitization.
Ning Gao   +4 more
doaj   +3 more sources

Does Electroacupuncture Have Different Effects on Peripheral and Central Sensitization in Humans: A Randomized Controlled Study

open access: yesFrontiers in Integrative Neuroscience, 2019
BackgroundAcupuncture is used to reduce chronic musculoskeletal pain. The common mechanism underlying these types of pain are peripheral and/or central sensitization.
Zhen Zheng   +4 more
doaj   +3 more sources

NSAIDs and Triptans – a (not) New Treatment Option for Migraine

open access: yesNeurologijos seminarai, 2023
Every day, around 7% of population will experience headache caused by migraine. Migraine is one of the leading causes of years lived with disability, and it also causes significant negative economic impact, as most as the affected population is of ...
B. Kakta, Rasa Mameniškienė
doaj   +3 more sources

Pressure Pain Thresholds and Central Sensitization in Relation to Psychosocial Predictors of Chronicity in Low Back Pain

open access: yesDiagnostics, 2023
(1) Background: Peripheral, as well as central, sensitization have been described in chronic low back pain (cLBP). The purpose of this study is to investigate the influence of psychosocial factors on the development of central sensitization. (2) Methods:
Anke Steinmetz   +2 more
doaj   +1 more source

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