Results 31 to 40 of about 707,409 (240)

Peripheral contrast sensitivity and attention in myopia

Vision Research, 2016
Disruption of normal visual experience or changes in the normal interaction between central and peripheral retinal input may lead to the development of myopia. In order to examine the relationship between peripheral contrast sensitivity and myopia, we manipulated attentional load for foveal vision in emmetropes and myopes while observers detected ...
Kristen L, Kerber, Frank, Thorn, Peter J, Bex, Fuensanta A, Vera-Diaz   +3 more
openaire   +2 more sources

A QSAR classification model of skin sensitization potential based on improving binary crow search algorithm [PDF]

, 2020
Classifying of skin sensitization using the quantitative structure-activityrelationship (QSAR) model is important. Applying descriptor selection isessential to improve the performance of the classification task.
Algamal, Zakariya Yahya; University of Mosul, Abdallh, Ghada Yousif; Northern Technical University   +1 more
core   +1 more source

Sensitivity to disparity corrugations in peripheral vision

Vision Research, 1998
Disparity discrimination thresholds are known to increase with both retinal eccentricity and distance from the horopter. However, little is known about how the detectability of cyclopean gratings varies with retinal position. Thresholds for disparity corrugations were measured as a function of corrugation frequency for different visual eccentricities ...
Prince, Simon J.D, Rogers, Brian J
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Peripheral and Central Sensitization

, 2017
Neuronal excitation in nociception is not a static process of the kind “same stimulus–same response,” but rather underlies dynamic plasticity to adapt to different situations. (pain due to a stimulus that does not usually provoke pain) and (increased pain from a stimulus that usually provokes pain) both exemplify these dynamic changes, and are the ...
Daniel Vardeh, Julian F. Naranjo
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Emerging roles of keratinocytes in nociceptive transduction and regulation

Frontiers in Molecular Neuroscience, 2022
Keratinocytes are the predominant block-building cells in the epidermis. Emerging evidence has elucidated the roles of keratinocytes in a wide range of pathophysiological processes including cutaneous nociception, pruritus, and inflammation ...
Xiaohan Xu, Catherine Yu, Catherine Yu, Catherine Yu, Li Xu, Jijun Xu, Jijun Xu, Jijun Xu   +7 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Peripheral cone contrast sensitivity in glaucoma

Vision Research, 1995
Colour vision tests for detection of glaucomatous damage frequently suffer from two problems: most tests are confined to foveal vision, whereas defects tend to appear first extrafoveally; and the modulation directions in colour space are not optimal. This paper deals with peripheral testing à la Yu, Falcao-Reis, Spileers and Arden [(1991) Investigative
Felius, Joost, Van den Berg, Thomas J.T.P., Spekreijse, Henk   +2 more
openaire   +2 more sources

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy [PDF]

, 2015
BACKGROUND: History and severity of atopic dermatitis (AD) are risk factors for peanut allergy. Recent evidence suggests that children can become sensitized to food allergens through an impaired skin barrier.
Sicherer, Scott, Brough, Helen A., Makinson, Kerry, Burks, Wesley, Turcanu, Victor, Jones, Stacie M., Liu, Andrew H., Lack, Gideon, Brown, Sara J., Sampson, Hugh, Wood, Robert A., Douiri, Abdel; id_orcid, Stablein, Donald, Dawson, Peter, Douiri, Abdel, McLean, W. H. Irwin, Stephens, Alick C., Irwin McLean, W.H.   +17 more
core   +1 more source