Results 11 to 20 of about 6,129,726 (293)

The neurobiology of central sensitization [PDF]

open access: yesJournal of Applied Biobehavioral Research, 2018
Central sensitization refers to the amplification of pain by central nervous system mechanisms. Classically described as a consequence of ongoing nociceptive input, it is increasingly recognized that central sensitization also occurs independent of ...
Clauw, Daniel J.   +5 more
core   +4 more sources

Central sensitization and pain hypersensitivity: Some critical considerations. [version 2; referees: 2 approved] [PDF]

open access: yesF1000Research, 2018
Since its discovery, central sensitization has gained enormous popularity. It is widely used to explain pain hypersensitivity in a wide range of clinical pain conditions.
Emanuel N. van den Broeke
doaj   +2 more sources

Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis [PDF]

open access: yesPain Research and Management, 2017
Dysregulation of Autonomic Nervous System (ANS) and central pain pathways in temporomandibular disorders (TMD) is a growing evidence. Authors include some forms of TMD among central sensitization syndromes (CSS), a group of pathologies characterized by ...
Annalisa Monaco   +4 more
doaj   +2 more sources

Peripheral and central sensitization [PDF]

open access: yesRevista Dor, 2016
BACKGROUND AND OBJECTIVES: Central sensitization is an important phenomenon for pain chronicity and is present in neuropathic pain. This study aimed at addressing some pathophysiological aspects of this phenomenon. CONTENTS: Some extra and intracellular
Hazem Adel Ashmawi   +1 more
doaj   +3 more sources

Central sensitization: a pathogenic mechanism in complex undefined diseases [PDF]

open access: yes, 2020
There is a common perception that complex undefined diseases manifested with diverse combination of symptoms and a difficult clinical diagnosis have a possible common physiological mechanism of disease production.
Fernández-Solà, J. (Joaquim)
core   +6 more sources

Central sensitivity and fibromyalgia [PDF]

open access: yesInternal Medicine Journal, 2021
AbstractFibromyalgia presents with symptoms of widespread pain, fatigue, sleeping and cognitive disturbances as well as other somatic symptoms. It often overlaps with other conditions termed ‘central sensitivity syndromes’, such as irritable bowel syndrome, chronic fatigue syndrome and temporomandibular disorder.
Veronica Mezhov   +2 more
openaire   +2 more sources

Central sensitization [PDF]

open access: yesThe Journal of Pain, 2004
B. Binns   +3 more
  +8 more sources

Metabolomics in Central Sensitivity Syndromes [PDF]

open access: yesMetabolites, 2020
Central sensitization syndromes are a collection of frequently painful disorders that contribute to decreased quality of life and increased risk of opiate abuse. Although these disorders cause significant morbidity, they frequently lack reliable diagnostic tests.
Joseph S. Miller   +2 more
openaire   +3 more sources

Trends in cutaneous sensitization in the first 18 years of life: results from the 1989 Isle of Wight birth cohort study [PDF]

open access: yes, 2012
Background:Skin prick testing (SPT) is fundamental to the practice of clinical allergy identifying relevant allergens and predicting the clinical expression of disease.
Raza, A.   +17 more
core   +1 more source

Pain‐autonomic interaction: A surrogate marker of central sensitization [PDF]

open access: yes, 2020
BACKGROUND: Central sensitization represents a key pathophysiological mechanism underlying the development of neuropathic pain, often manifested clinically as mechanical allodynia and hyperalgesia.
Hubli, Michèle   +7 more
core   +1 more source

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