Results 91 to 100 of about 5,625 (181)

Disease Stage and Motor Fluctuation Duration Predict Drug Tolerability: A Real-Life, Prospective Italian Multicenter Study on the Use of Opicapone in Parkinson’s Disease

Drugs - Real World Outcomes
Background Opicapone is a third-generation catechol-O-methyl-transferase inhibitor currently used for the treatment of motor fluctuations in Parkinson’s disease. Its benefit and safety have been established by clinical trials; however, data about its use
Ruggero Bacchin, Marco Liccari, Mauro Catalan, Lucia Antonutti, Paolo Manganotti, Maria Chiara Malaguti, Bruno Giometto   +6 more
doaj   +1 more source

Sensorial activity determination of the human catechol-O-methyl transferase at fluorine doped tin oxide

, 2020
Gero Göbel, Anja Talke, Uwe Ahnert, Fred Lisdat   +3 more
openalex   +2 more sources

Current approaches to the treatment of Parkinson’s disease

Neuropsychiatric Disease and Treatment, 2008
Joseph Jankovic, L Giselle AguilarParkinson’s Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of MedicineAbstract: Enormous progress has been made in the treatment of Parkinson’s disease (PD).
Joseph Jankovic, L Giselle Aguilar
doaj  

Genetic predictors of attempted suicide among South Indian adolescents and young adults: A case-control study

Biomarkers in Neuropsychiatry
Background: Suicide among adolescents and young adults is an alarming public health issue globally. Though studies suggest the link between genetic factors and suicidal behavior, there is a paucity of studies of specific genetic variants in adolescents ...
Anju Mathew, Ann Mary Alex, Chathathayil Mohammedali Shafeeque, Saboora Beegum Muthubeevi, Vijayakumar Krishnapillai, Moinak Banerjee   +5 more
doaj   +1 more source

The association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and morphological abnormalities of the brain in chronic schizophrenia [PDF]

, 2005
Takashi Ohnishi, Ryota Hashimoto, Takeyuki Mori, Kiyotaka Nemoto, Yoshiya Moriguchi, Hidehiro Iida, Hiroko Noguchi, Tetsuo Nakabayashi, Hiroaki Hori, Mayu Ohmori, R. Tsukue, Kimitaka Anami, Naotugu Hirabayashi, Seiichi Harada, Kunimasa Arima, Osamu Saitoh, Hiroshi Kunugi   +16 more
openalex   +1 more source

Expression of Catechol O methyl transferase (COMT) with the contrasting effects of 17β estradiol (E2): Implications for the mechanism of estrogen-induced ovarian carcinogenesis. [PDF]

, 2020
Nour El-Etreby, Eman Medhat Osman, Nehal Abd El Latif El Badawy, Hoda A. Nour   +3 more
openalex   +1 more source

Association of Lower COMT Activity Alleles with Aggressive Traits in Male Youth with Conduct Disorder Living in a Correctional Facility

Biomolecules
Aggression constitutes a significant behavioral issue associated with delinquent behavior, commonly observed in youth diagnosed with conduct disorder (CD) and living in correctional facilities.
Lucija Tudor, Josip Podobnik, Gordana Nedic Erjavec, Matea Nikolac Perkovic, Jaanus Harro, Margus Kanarik, Darko Marcinko, Dubravka Svob Strac, Melita Cusek, Vlatka Kovac, Nela Pivac   +10 more
doaj   +1 more source

Genetic analysis of catechol-O-methyl transferase in Alzheimer's disease

Neurologia Croatica. Supplement, 2006
Alzheimer's disease (AD) is a growing public health problem, the major risk for dementia, frequently associated with psychotic symptoms. The causes of AD are still unknown, and it is assumed that various etiologies lead to the characteristic pathological changes. Around 5-10% of AD is influenced by genetic factors. The aim of the study was to determine
Mimica, Ninoslav, Muck-Šeler, Dorotea, Deželjin, Martina, Pivac, Nela, Mustapić, Maja, Folnegović-Šmalc, Vera   +5 more
openaire   +1 more source

Lack of association between COMT gene polymorphism and treatment outcome in major depression

Psychiatry and Behavioral Sciences, 2011
Background & Aim: Abnormal activity of Catechol-O-methyl transferase (COMT), as a major degrading enzyme of catecholaminergic neurotransmitters may be enrolled in the pathogenesis of mood disorders.
Salih Selek, Mehmet C. Kaya, Mehmet Emin Erdal, Mahmut Bulut, Murat Eren Ozen, Mehmet Yumru, Omer Barlas, Aysun Kalenderoglu, Hasan Herken   +8 more
doaj  

Dietary Magnesium Insufficiency Induces Salt-Sensitive Hypertension in Mice Associated With Reduced Kidney Catechol-O-Methyl Transferase Activity [PDF]

, 2021
Asako Kumagai, Satoru Takeda, Eisei Sohara, Shinichi Uchida, Hiroshi Iijima, Atsuo Itakura, Daisuke Koya, Keizo Kanasaki   +7 more
openalex   +1 more source