Results 11 to 20 of about 5,625 (181)

Catechol-O-methyl Transferase in Epidermis, Dermis and Whole Skin*

open access: bronzeJournal of Investigative Dermatology, 1969
The presence of catechol-o-methyl transferase (COMT), an enzyme involved in the major route of inactivation of epinephrine and norepinephrine (1), has been established in normal skin (2). Skin includes both epidermis and MATERIALS AND METHODS Normal skin was obtained from the operating room and was placed on crushed ice.
Jalal Bamshad
openalex   +3 more sources

Electrochemical Activity Determination of Catechol‐O‐methyl Transferase by Selective Dopamine Detection [PDF]

open access: hybridChemElectroChem, 2019
AbstractFor the treatment of Parkinson's disease, as one of the most frequent diseases of the central nervous system, several key enzymes for dopamine metabolism [e. g. catechol‐O‐methyl transferase (COMT)] are drug targets. For an efficient and long‐lasting treatment, the activity of this enzyme should be monitored.
Gero Göbel   +3 more
openalex   +4 more sources

Effects of estrogen on human catechol-O-methyl transferase

open access: gold, 2001
published_or_final_version ; Medicine ; Doctoral ; Doctor of ...
Hong Jiang
openalex   +3 more sources

Myocardial Catechol-O-Methyl Transferase Activity after Chronic Cardiac Denervation [PDF]

open access: bronzeNature, 1962
IN a recent study of the denervated dog heart1, we noted a marked increase in cardiac sensitivity to norepinephrine, a finding anticipated from previous investigations of denervated organs2. Catechol-O-methyl transferase activity was measured in these denervated hearts to determine whether this pharmacological supersensitivity might be accompanied by a
J. Richard Crout, Theodore Cooper
openalex   +3 more sources

Prefrontal white matter impairment in substance users depends upon the catechol-o-methyl transferase (COMT) val158met polymorphism. [PDF]

open access: greenNeuroimage, 2013
Zhang X   +12 more
europepmc   +3 more sources

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