Results 81 to 90 of about 5,625 (181)
Trends in Antiparkinsonian Medication Use in New Zealand: 1995–2011
Parkinson's Disease, 2014 Prescribing trends for medications are influenced by development of new drugs, changes in knowledge about efficacy and side effects, and priorities set by funding agencies. Changes in the utilization of antiparkinsonian agents in the outpatient community
T. L. Pitcher +2 more
doaj +1 more source
Opicapone, a Novel Catechol-O-methyl Transferase Inhibitor, for Treatment of Parkinson's Disease "Off" Episodes. [PDF]
Health Psychol Res, 2022 Berger AA +11 more
europepmc +1 more source
Brazilian Journal of Psychiatry, 2015 Objective:To assess the relationship between cognitive function, a proposed schizophrenia endophenotype, and two genetic polymorphisms related to dopamine function, catechol-O-methyl transferase (COMT) Val158Met and dopamine receptor 3 (DRD3) Ser9Gly ...
Alexandre A. Loch +8 more
doaj +1 more source
Неврология, нейропсихиатрия, психосоматика, 2019 Objective: to study the association of the polymorphic genotypes of rs4680 in the catechol-O-methyl transferase (COMT) gene with vital exhaustion (VE) in a 45–64-year-old population. Patients and methods.
V. V. Gafarov +6 more
doaj +1 more source
Association of the Catechol-O-Methyl Transferase Gene Val158Met Polymorphism With Blood Pressure and Prevalence of Hypertension: Interaction With Dietary Energy Intake [PDF]
, 2011 Nay Chi Htun +5 more
openalex +1 more source
Scientific ReportsWe assessed the effect of the 5-HT1A receptor (R) antagonist WAY100,635 on motor behaviors, object place learning and the regional levels of dopamine (DA), serotonin (5-HT) and their metabolites in the rat brain. After a single dose of either WAY100,635 (
Benedetta Fazari +13 more
doaj +1 more source
Effect of Tumour Necrosis Factor-Alpha on Estrogen Metabolic Pathways in Breast Cancer Cells
Journal of Cancer, 2012 Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that has been linked to breast cancer development. Estrogen metabolic pathway is also involved in breast carcinogenesis and DNA adducts formation.
Marwa Kamel, Samia Shouman, Mahmoud El-Merzebany, Gokhan Kilic, Timothy Veenstra, Muhammad Saeed, Mohamed Wagih, Concepcion Diaz-Arrastia, Deepa Patel, Salama Salama
doaj
Review: Improving symptom control in early Parkinson’s disease
Therapeutic Advances in Neurological Disorders, 2009 Motor symptoms in Parkinson’s disease (PD) are caused by a severe loss of pigmented dopamine-producing nigro-striatal neurons. Symptomatic therapies provide benefit for motor features by restoring dopamine receptor stimulation.
Stuart H. Isaacson, Robert A. Hauser
doaj +1 more source
Neuroleptic malignant-like syndrome in an elderly patient caused by abrupt withdrawal of tolcapone, a catechol-O-methyl transferase inhibitor [PDF]
, 2000 Cletus U Iwuagwu +2 more
openalex +1 more source