Parkinson's disease is a global health challenge affecting over 10 million individuals worldwide, leading to increased disability-adjusted life years (DALYs) and a rise in mortality rates. This study explores the potential anti-Parkinson's properties of
Riyan Alifbi Putera Irsal +4 more
doaj +1 more source
Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
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Introduction: Attention-deficit hyperactivity disorder (ADHD) is a common polygenic heritable disorder. We have investigated the relationship between ADHD and polymorphisms of catechol-O-methyltransferase (COMT) and monoaminooxidase B (MAOB) genes. It is
Pavel Theiner +6 more
doaj
Interaction of catechol O-methyltransferase and serotonin transporter genes modulates effective connectivity in a facial emotion-processing circuitry [PDF]
Simon Surguladze +8 more
openalex +1 more source
Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders. [PDF]
Methylphenidate (MPH) reduces hyperactive-impulsive symptoms common in children with autism spectrum disorders (ASDs), however, response and tolerability varies widely.
Aman, MG +13 more
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Association Between the Catechol-O-Methyltransferase Val158Met Polymorphism and Cocaine Dependence [PDF]
Falk W. Lohoff +10 more
openalex +1 more source
Assessment of Metabolic Parameters For Autism Spectrum Disorders [PDF]
Autism is a brain development disorder that first appears during infancy or childhood, and generally follows a steady course without remission. Impairments result from maturation-related changes in various systems of the brain.
Ghosh, S +4 more
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Simulating Enzyme Catalysis [PDF]
Chemistry is about transformations between compounds as the result of forming and breaking bonds between their atoms. A detailed knowledge of these processes should open the door to one of the most desired goals in this field, which is the ...
Moliner, Vicent, Tuñón, Iñaki
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Unraveling Catechol-O-Methyltransferase rs4680 SNP's Role in Patients' Response to Tramadol and Its Adverse Effects: A Pharmacogenetics Insight into Postoperative Pain Management. [PDF]
Khan A +5 more
europepmc +1 more source
Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype. [PDF]
PMID: 28195063Catechol-O-methyltransferase (COMT) has two isoforms: soluble (S-COMT), which resides in the cytoplasm, and membrane-bound (MB-MT), anchored to intracellular membranes.
Aonurm-Helm, Anu +6 more
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