Results 181 to 190 of about 78,308 (305)

Microbial Lignin Valorization to Protocatechuic Acid and Catechol: Biofunneling Pathways and Metabolic Engineering Strategies. [PDF]

Biomolecules
Kamaraj Y, Ali S, Sivasamy S, Dar MA, Le G, Rani A, Kumaresan V, Ahmad N, Zhu D.   +8 more
europepmc   +1 more source

Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa remains the most effective pharmacological treatment for Parkinson's disease (PD), but long‐term use commonly leads to motor complications such as levodopa‐induced dyskinesia (LID) and motor fluctuations, significantly contributing to disability. Exercise is well‐established for improving motor and non‐motor symptoms in PD;
Priscila Nóbrega‐Sousa, Lucas H.C.C. Santos, Jane Alty, Peter Humburg, Kim Delbaere, Paulo H.S. Pelicioni   +5 more
wiley   +1 more source

Siderophore-Enabled Delivery of Carbapenem and Metallo-β-Lactamase Inhibitor: A Promising Strategy against Multidrug-Resistant Pseudomonas aeruginosa. [PDF]

J Am Chem Soc
Safari S, Petrov R, Ustimenko YP, Jeannot K, Trivelli X, Anoz-Carbonell E, Hartkoorn RC.   +6 more
europepmc   +1 more source

Transmetallic biomimetic Hydrogel implants restore osteogenesis-angiogenesis coupling via Fe/Co ionic microenvironment remodeling for enhancing osteoporotic fracture healing. [PDF]

Bioact Mater
Wei H, Hu X, Chen M, Tan L, Li M, Luo Z, Cai K, Hu Y.   +7 more
europepmc   +1 more source

Ursodeoxycholic Acid and Parkinson's Disease Risk: An Emulated Target Trial in UK Electronic Health Records

Movement Disorders, EarlyView.
Abstract Background Ursodeoxycholic acid (UDCA) has shown mitochondrial and neuroprotective effects and has been proposed as a treatment for Parkinson's disease (PD). However, population‐level evidence on its effect on PD risk is lacking. Objectives To compare the risk of incident PD among UDCA initiators versus matched non‐initiators within a ...
Chengsheng Ju, Anette Schrag, Camille Carroll, Xi Xiong, James Carpenter, Oliver Bandmann, Thomas Foltynie, Li Wei   +7 more
wiley   +1 more source

Synergistic Co-Zn dual atomic sites drive C-lignin hydrogenolysis via vicinal C-O cleavage. [PDF]

Nat Commun
Li X, Xia Y, Ma Y, Liu J, Ma Y, Wang S, Lu Q, Song G.   +7 more
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Serum-Integrated Dopamine-Hyaluronic Acid Hydrogels for Injectable Soft-Tissue Microenvironment Modulation. [PDF]

Macromol Biosci
Quan VM, Nguyen Thi TK, Le KL, Nguyen-Ngoc BH, Le Thi P, Le KM, Le Tran MA, Doan HN, Nguyen TH.   +8 more
europepmc   +1 more source

Therapeutic Impact of GLP‐1 Receptor Agonists on Parkinson's Disease: A Scoping Review

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT No disease‐modifying treatment exists for Parkinson's disease (PD). Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have gained attention as promising candidates for neuroprotection, given documented expression of GLP‐1 receptors within the central nervous system and the contribution of brain insulin resistance to dopaminergic ...
João Pedro Henriques, João Pedro Stringhetta Rahal, Rafael da Cunha Gomes Ribeiro, Enzo Bogucheski Ribeiro Machado, Carlos Antonio Negrato   +4 more
wiley   +1 more source

Rigorous Modeling and Industrial-Scalable Optimization of Hydroquinone-Catechol Vacuum Distillation: Aspen Plus-RSM Integration for Thermally Labile Systems. [PDF]

ACS Omega
Wang C, Zeng Y, Yi M, Yang M, Qiu S, Xie Y, Cai P.   +6 more
europepmc   +1 more source