Results 161 to 170 of about 54,961 (264)

Advances in the Chemical Properties and Functional Applications of Urushiol: From Traditional Lacquerware to Modern Materials. [PDF]

Polymers (Basel)
Xu S, Liu Y, Chen W, Zhang J, Liu X.
europepmc   +1 more source

Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe, Sergio García‐Díaz, Laura Muñoz‐Delgado, Miguel Martín‐Bórnez, Silvia Jesús, Dolores Buiza‐Rueda, Marta Bonilla‐Toribio, Rafael Díaz‐Belloso, Daniel Macías‐García, Astrid Adarmes‐Gómez, Antonio Luque‐Ambrosiani, Rocío Pineda‐Sánchez, Lorena Clavijo‐Jiménez, Fátima Carrillo‐García, Pilar Gómez‐Garre, Pablo Mir   +15 more
wiley   +1 more source

Adhesive Hydrogels as Fixation and Regeneration Platforms in Cartilage Surgery: Rethinking Scaffold-Tissue Integration from a Clinical Perspective. [PDF]

Int J Mol Sci
Jo H, Lee SS.
europepmc   +1 more source

Impact of Low-Dose Cranberry Polyphenols on Gut Microbiota and Circulating Polyphenol Metabolites in Overweight and Obese Individuals (A Randomized Double-Blind Placebo-Controlled Clinical Pilot Study). [PDF]

Food Sci Nutr
Castellon MJC, Jang MJ, Diaz MS, Haque MA, Talcott ST, Ku S, Mertens-Talcott SU.   +6 more
europepmc   +1 more source

Exercise and Motor Complications in Parkinson's Disease: A Systematic Review and Meta‐Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Levodopa remains the most effective pharmacological treatment for Parkinson's disease (PD), but long‐term use commonly leads to motor complications such as levodopa‐induced dyskinesia (LID) and motor fluctuations, significantly contributing to disability. Exercise is well‐established for improving motor and non‐motor symptoms in PD;
Priscila Nóbrega‐Sousa, Lucas H.C.C. Santos, Jane Alty, Peter Humburg, Kim Delbaere, Paulo H.S. Pelicioni   +5 more
wiley   +1 more source

Investigating catechol adsorption to the ZnO (101̄0) surface with and without an oxygen vacancies using the DFT-D2 method. [PDF]

RSC Adv
Kamal N, De AK, Shrivastava A, Sinha I.
europepmc   +1 more source

Structure-guided discovery of non-catechol dopamine D1 receptor ligands with biased agonism and antagonism. [PDF]

J Biol Chem
Zhou Y, Wetsel WC, Kahsai AW, Olson SH, Barak LS.   +4 more
europepmc   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Genomic and functional insights into aromatic compound degradation by <i>Delftia</i> strain PS-11 isolated from freshwater pufferfish. [PDF]

Microbiol Spectr
Archana Kujur RR, Deb S, Debnath T, Papade S, Phale PS, Das SK.   +5 more
europepmc   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source