Results 51 to 60 of about 78,308 (305)

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

Advanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn, Wenjing Wang, Yao Qin, Lili Yan, Stephan Scheeff, Xu He, Qiong Wu, Yue Lin, Jinsai Shang, Xin Ye, Jing Liu, Kailei Sun, Chun Wai Yeung, Junzhe Huang, Zhenghui Chen, Xiaodong Liu, Yiqun Geng, Shannon Wing Ngor Au, Bonaventure Y. Ip, Ho Ko, Billy Wai‐Lung Ng   +20 more
wiley   +1 more source

Template-Assisted Formation of Nanostructured Dopamine-Modified Polymers

Nanomaterials, 2017
Dopamine-modified alginate and gelatin were prepared. The polymers were characterized and the properties of their aqueous solutions were investigated.
Liping Zhu, Takashi Isoshima, Baiju G. Nair, Yoshihiro Ito   +3 more
doaj   +1 more source

Triphenylantimony(V) Catecholates of the Type (3-RS-4,6-DBCat)SbPh₃-Catechol Thioether Derivatives: Structure, Electrochemical Properties, and Antiradical Activity

Molecules, 2021
A new series of triphenylantimony(V) 3-alkylthio/arylthio-substituted 4,6-di-tert-butylcatecholates of the type (3-RS-4,6-DBCat)SbPh3, where R = n-butyl (1), n-hexyl (2), n-octyl (3), cyclopentyl (4), cyclohexyl (5), benzyl (6), phenyl (7), and naphthyl ...
Ivan V. Smolyaninov, Georgy K. Fukin, Nadezhda T. Berberova, Andrey I. Poddel’sky   +3 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Identification and Quantitation of ¹⁴C-Labeled Catechol Metabolites in Rat Plasma After Intranasal Instillation of Smoldering Eucalyptus Wood Smoke Extract

Methods and Protocols
The increasing frequency, duration, and intensity of wildfires over the past decade have raised significant concerns about widespread exposure to wildfire smoke.
David Baliu-Rodriguez, Dorothy J. You, Michael A. Malfatti, Esther A. Ubick, Yong Ho Kim, Bruce A. Buchholz   +5 more
doaj   +1 more source

Synthesis of Polar Aromatic Substituted Terminal Alkynes from Propargyl Amine

Molbank, 2021
A series of small molecules containing polar aromatic substituents and alkynes have been synthesized. One–pot preparations of polar aromatic molecules containing an alkynyl imine and alkynyl amide are reported.
Surya R. Banks, Kyung Min Yoo, Mark E. Welker   +2 more
doaj   +1 more source

Effect of Catechol Content in Catechol-Conjugated Dextrans on Antiplatelet Performance [PDF]

Polymers, 2017
The surface coating of solid substrates using dextrans has gained a great deal of attention, because dextran-coated surfaces show excellent anti-fouling property as well as biocompatibility behavior. Much effort has been made to develop efficient methods for grafting dextrans on solid surfaces.
Yeonwoo Jeong, Kwang-A Kim, Sung Kang
openaire   +2 more sources

Bioinspired Self-Healing Hydrogel Based on Benzoxaborole-Catechol Dynamic Covalent Chemistry for 3D Cell Encapsulation [PDF]

, 2018
Boronic ester, one typical example of dynamic covalent bonds, has presented great potential to prepare self-healing hydrogels. However, most of currently reported hydrogels based on boronic esters are formed at pH > 8, which impeded their further use ...
Peng, Yi-Yang, Wang, Wenda, Ishihara, Kazuhiko, Asha, Anika Benozir, Chen, Yangjun, Hall, Dennis G., Narain, Ravin, Diaz-Dussan, Diana, Wu, Di   +8 more
core   +1 more source

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

Advanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao, Lijun Fan, Yunyuan Dong, Xuyu Bao, Xiaobin Chen, Qifu Zheng, Guanqing Zhang, Shen Wang, Wei Chen, Min Zhang, Shuaiming He   +10 more
wiley   +1 more source

Bioconversion of Biomass-Derived Phenols Catalyzed by Myceliophthora thermophila Laccase

Molecules, 2016
Biomass-derived phenols have recently arisen as an attractive alternative for building blocks to be used in synthetic applications, due to their widespread availability as an abundant renewable resource.
Anastasia Zerva, Nikolaos Manos, Stamatina Vouyiouka, Paul Christakopoulos, Evangelos Topakas   +4 more
doaj   +1 more source