Results 1 to 10 of about 187,485 (290)

CUDC-907, a dual PI3K/histone deacetylase inhibitor, increases meta-iodobenzylguanidine uptake (123/131I-mIBG) in vitro and in vivo: a promising candidate for advancing theranostics in neuroendocrine tumors

Journal of Translational Medicine, 2023
Background Neuroblastoma (NB) and pheochromocytoma/paraganglioma (PHEO/PGL) are neuroendocrine tumors. Imaging of these neoplasms is performed by scintigraphy after injection of radiolabeled meta-iodobenzylguanidine (mIBG), a norepinephrine analog taken ...
Joana Grand-Guillaume, Rosalba Mansi, Raghuvir H. Gaonkar, Sandra Zanger, Melpomeni Fani, Philippe J. Eugster, Maja Beck Popovic, Eric Grouzmann, Karim Abid   +8 more
doaj   +1 more source

A new 68Ga-labeled somatostatin analog containing two iodo-amino acids for dual somatostatin receptor subtype 2 and 5 targeting

EJNMMI Research, 2020
Background Somatostatin receptor (SST) targeting, specifically of the subtype 2 (SST2), with radiolabeled somatostatin analogs, is established for imaging and treatment of neuroendocrine tumors.
Rosalba Mansi, Karim Abid, Guillaume P. Nicolas, Luigi Del Pozzo, Eric Grouzmann, Melpomeni Fani   +5 more
doaj   +1 more source

Serial Hydrolysis for the Simultaneous Analysis of Catecholamines and Steroids in the Urine of Patients with Alopecia Areata

Molecules, 2021
Catecholamines and steroids are well-known neurotransmitters and hormones that rapidly change the excitability of neurons. Alopecia areata is a disease for which the exact cause is unknown, but it is considered to be associated with stress, and so the ...
Yu-Ra Lee, Bark-Lynn Lew, Woo-Young Sim, Jongki Hong, Bong-Chul Chung   +4 more
doaj   +1 more source

Inflammatory response modulation by epinephrine and norepinephrine

RUDN Journal of Medicine, 2023
Relevance. Inflammation is a defense response of an organism to a pathogen. It appears in order to maintain homeostasis and is regulated by the immune, nervous, and endocrine systems.
Svetlana V. Guryanova, Artem S. Ferberg, Ilya A. Sigmatulin   +2 more
doaj   +1 more source

Evaluation of a New ¹⁷⁷Lu-Labeled Somatostatin Analog for the Treatment of Tumors Expressing Somatostatin Receptor Subtypes 2 and 5

Molecules, 2020
Targeted radionuclide therapy of somatostatin receptor (SST)-expressing tumors is only partially addressed by the established somatostatin analogs having an affinity for the SST subtype 2 (SST2).
Rosalba Mansi, Guillaume Pierre Nicolas, Luigi Del Pozzo, Karim Alexandre Abid, Eric Grouzmann, Melpomeni Fani   +5 more
doaj   +1 more source

Clinical differences between small and large pheochromocytomas and paragangliomas

Frontiers in Endocrinology, 2023
BackgroundPheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors, most of which are characterized by the release of catecholamine, and range in diameters from less than 1 cm to 10 cm or more.
Lin Zhao, ZhiMao Li, Xu Meng, Hua Fan, ZengLei Zhang, ZhaoCai Zhang, YeCheng Liu, XianLiang Zhou, HuaDong Zhu   +8 more
doaj   +1 more source

Anesthetic management of urinary bladder paraganglioma

Bali Journal of Anesthesiology, 2020
Extra-adrenal paraganglioma is a rare neuroendocrine tumor that produces stores and secretes catecholamine. The mainstay in the management of the patients posted for resection of these tumors includes adequate preoperative preparation, good collaboration
Priyanka Singh, Jasvinder Kohli, M D Kaur   +2 more
doaj   +1 more source

Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension

Frontiers in Endocrinology, 2022
IntroductionNeuroblastoma (NB) is a pediatric cancer of the developing sympathetic nervous system. It produces and releases metanephrines, which are used as biomarkers for diagnosis in plasma and urine. However, plasma catecholamine concentrations remain
Annick Mühlethaler-Mottet, Silvia Uccella, Silvia Uccella, Deborah Marchiori, Stefano La Rosa, Stefano La Rosa, Jean Daraspe, Katia Balmas Bourloud, Maja Beck Popovic, Philippe J. Eugster, Eric Grouzmann, Karim Abid   +11 more
doaj   +1 more source

Expression of the Tyrosine Hydroxylase Gene from Rat Leads to Oxidative Stress in Potato Plants

Antioxidants, 2020
Catecholamines are biogenic aromatic amines common among both animals and plants. In animals, they are synthesized via tyrosine hydroxylation, while both hydroxylation or decarboxylation of tyrosine are possible in plants, depending on the species ...
Kamil Kostyn, Aleksandra Boba, Anna Kostyn, Bartosz Kozak, Michał Starzycki, Anna Kulma, Jan Szopa   +6 more
doaj   +1 more source

A case report and literature review: pheochromocytoma-mediated takotsubo cardiomyopathy, which is similar to acute myocardial infarction

Frontiers in Cardiovascular Medicine, 2023
A 52-year-old Chinese woman was admitted to a cardiac intensive care unit (CCU) due to nausea, vomiting, and dyspnea, which began a day before her hospitalization. Metoprolol succinate and conventional treatment for acute myocardial infarction (AMI) were
Zhiyu Zhang, Xia Guo, Jingyue Wang, Shipeng Wang, Yushi Wang   +4 more
doaj   +1 more source