Structure mirroring function: What's the ‘matter’ with the funny current?
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
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Japan Endocrine Society Clinical Practice Guideline for the Diagnosis and Management of Pheochromocytoma and Paraganglioma 2025. [PDF]
Tanabe A +22 more
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Abstract figure legend Catecholaminergic polymorphic ventricular tachycardia (CPVT) variants in N terminal (NTD) and central domain (CD) but not pore domain induce a pathological RyR2 conformational shift upon protein kinase A (PKA) phosphorylation, similar to that seen in heart failure (HF), calcium/calmodulin‐dependent protein kinase II (CaMKII ...
Hitoshi Uchinoumi +11 more
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Pheochromocytoma-Induced Leukocytosis With Concurrent Severe Eosinophilia: A Case Report. [PDF]
Alnaqeeb N +3 more
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Caffeine in cerebrovascular research: To withdraw or not to withdraw?
Experimental Physiology, EarlyView.
Brooke R. Shepley +2 more
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Repolarization adaptation to rapid change in heart rate in human models – a review
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt +5 more
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Biochemically 'active' pheochromocytoma can be clinically 'silent'. [PDF]
Patra S, Choube A, Munjewar C, Mitra S.
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Silent adrenal pheochromocytoma coexistent with corticomedullary hyperplasia: a case incidentally discovered [PDF]
Antonio, Ciardi +7 more
core
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche +13 more
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Takotsubo syndrome with apical thrombosis associated with hyperthyroidism crisis: a case report from high-altitude Tibet. [PDF]
Zhang J, Yin L, Zhang Q.
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