Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley +1 more source
Takotsubo Syndrome and Oxidative Stress: Physiopathological Linkage and Future Perspectives. [PDF]
Mauriello A+12 more
europepmc +1 more source
Structure mirroring function: What's the ‘matter’ with the funny current?
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley +1 more source
Urinary Dopamine Levels Can Predict the Avidity of Post-Therapy [131I]MIBG Scintigraphy in Unresectable or Metastatic Pheochromocytomas and Paragangliomas: A Preliminary Clinical Study. [PDF]
Takenaka J+9 more
europepmc +1 more source
Abstract figure legend Catecholaminergic polymorphic ventricular tachycardia (CPVT) variants in N terminal (NTD) and central domain (CD) but not pore domain induce a pathological RyR2 conformational shift upon protein kinase A (PKA) phosphorylation, similar to that seen in heart failure (HF), calcium/calmodulin‐dependent protein kinase II (CaMKII ...
Hitoshi Uchinoumi+11 more
wiley +1 more source
Anesthetic Challenges of Labor and Delivery in a Patient With Catecholaminergic Polymorphic Ventricular Tachycardia and Left Ventricular Non-Compaction Cardiomyopathy. [PDF]
Jackson C+3 more
europepmc +1 more source
Repolarization adaptation to rapid change in heart rate in human models – a review
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt+5 more
wiley +1 more source
Pheochromocytoma-Induced Reversible Dilated Cardiomyopathy: A Case Report and Literature Review. [PDF]
Afra F+4 more
europepmc +1 more source
GATA Transcription Factors: A Cross‐Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies
ABSTRACT Alpha‐synuclein (α‐syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies.
Francesco Bellomi+7 more
wiley +1 more source
Metastatic Pheochromocytoma/Paraganglioma Overproducing Multiple Catecholamines. [PDF]
Yoshioka K+5 more
europepmc +1 more source