Deciphering the skeletal interoceptive circuitry to control bone homeostasis
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu+7 more
wiley +1 more source
Effect of lower sodium intake on health: systematic review and meta-analyses [PDF]
Objective To assess the effect of decreased sodium intake on blood pressure, related cardiovascular diseases, and potential adverse effects such as changes in blood lipids, catecholamine levels, and renal function.
Aburto, Nancy J.+5 more
core +1 more source
In situ biomimetic materials for dentin repair
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng+3 more
wiley +1 more source
All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters [PDF]
We report on the ion beam fabrication of all-carbon multi electrode arrays (MEAs) based on 16 graphitic micro-channels embedded in single-crystal diamond (SCD) substrates.
Battiato, A.+9 more
core +2 more sources
Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System
ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva+7 more
wiley +1 more source
A new common functional coding variant at the DDC gene change renal enzyme activity and modify renal dopamine function. [PDF]
The intra-renal dopamine (DA) system is highly expressed in the proximal tubule and contributes to Na+ and blood pressure homeostasis, as well as to the development of nephropathy.
Baker, Dewleen G+15 more
core +2 more sources
Ischaemic Heart Disease Masquerading as Headache: A Case Series
ABSTRACT Headache is a rare yet clinically significant presentation of ischaemic heart disease (IHD). While chest pain is the hallmark symptom of myocardial ischaemia (MI), some patients present with atypical symptoms, such as headaches, which lead to diagnostic challenges and potential delays in treatment.
Ibrahim Antoun+3 more
wiley +1 more source
ABSTRACT Background Coronary artery vasospasm following coronary artery bypass grafting (CABG) is a rare but potentially life‐threatening complication that can lead to myocardial ischemia, arrhythmias, and cardiogenic shock. Nitroglycerin‐resistant vasospasm, particularly involving the left main coronary artery (LMCA), poses significant diagnostic and ...
Dina Soliman+3 more
wiley +1 more source
Characterization of hormone and protein release from alpha-toxin- permeabilized chromaffin cells in primary culture [PDF]
Addition of Staphylococcus aureus alpha-toxin to adult bovine chromaffin cells maintained in primary culture causes permeabilization of cell membrane as shown by the release of intracellular 86Rb+.
Ahnert-Hilger, G.+4 more
core
Neuro-hormonal effects of physical activity in the elderly. [PDF]
Thanks to diagnostic and therapeutic advances, the elderly population is continuously increasing in the western countries. Accordingly, the prevalence of most chronic age-related diseases will increase considerably in the next decades, thus it will be ...
Allocca, E+12 more
core +1 more source