Results 271 to 280 of about 242,791 (386)

Exercise modality‐dependent mitochondrial respiratory capacity in satellite cells and conditioned serum‐induced responses in cultured myotubes

open access: yesExperimental Physiology, EarlyView.
Abstract Exercise‐induced mitochondrial adaptations contribute to muscle function and metabolic health. We aimed to investigate the association of moderate‐intensity swimming (MOD) and high‐intensity interval training (HIIT) with mitochondrial function in skeletal muscle cells treated with exercise‐conditioned serum.
Takanaga Shirai   +7 more
wiley   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

open access: yesExperimental Physiology, EarlyView.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings   +3 more
wiley   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

open access: yesExperimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su   +4 more
wiley   +1 more source

Exploring neuronal mechanisms of osteosarcopenia in older adults

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The mechanosensitive osteocytic network within the bone matrix acts as a receptor and plays a crucial role in the functional adaptation of bone to mechanical loading. Through mechanotransduction, osteocytes convert mechanical impulses into electrical signals, which are transmitted via afferent nerves to sympathetic preganglionic ...
Ilhan Karacan, Kemal Sıtkı Türker
wiley   +1 more source

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