Results 31 to 40 of about 159,102 (357)

Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland [PDF]

open access: yes, 2019
The evidence from post-mortem biochemical studies conducted on cortisol and catecholamines suggest that analysis of the adrenal gland could provide useful information about its role in human pathophysiology and the stress response.
Alibrandi A.   +10 more
core   +1 more source

SPLICEIT Fluorescent Sensor for Integrating Dopamine Release with Cellular Resolution

open access: yesAngewandte Chemie, EarlyView.
“Single‐chain protein‐based ligand indication through a chimerically‐engineered integrator tool” (SPLICEIT) is a G‐protein coupled receptor‐based sensor design that leaves a permanent fluorescent mark. We show dopamine detection in primary cultured neurons with a fourfold signal increase normalized to an mCherry (mCh) marker.
Steven M. Havens   +7 more
wiley   +2 more sources

Levosimendan for the prevention of acute organ dysfunction in sepsis [PDF]

open access: yes, 2016
BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...
Al-Beidh, F   +16 more
core   +2 more sources

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

THE PARTICIPATION OF CATECHOLAMINES IN THE PATHOGENESIS OF DIABETIC CARDIOMYOPATHY

open access: yesМедицина в Кузбассе, 2020
Under normal conditions, the sympathetic nervous system, through its main mediators (catecholamines) plays an important role in the functioning of the cardiovascular system.
Алексей Михайлович Чаулин   +2 more
doaj  

Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]

open access: yes, 1993
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J.   +5 more
core   +1 more source

Direct Surface Modification of the Epidermis Using Mussel‐Inspired Polydopamine with Multiple Anti‐Biofouling Functions

open access: yesAdvanced Healthcare Materials, EarlyView.
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee   +14 more
wiley   +1 more source

Brain death in ICU patients: Clinical significance of endocrine changes

open access: yesIndian Journal of Endocrinology and Metabolism, 2014
Numerous studies have been carried out among patients admitted in intensive care unit (ICU) having primary endocrine pathology, endocrine manifestations of systemic diseases or post-endocrine tissue surgery.
Sukhminder Jit Singh Bajwa   +1 more
doaj   +1 more source

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

open access: yesAdvanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Glucocorticoids and Catecholamines Affect in Vitro Functionality of Porcine Blood Immune Cells

open access: yesAnimals, 2019
Stress hormones exert important modulating influences on the functionality of immune cells. Despite its major role as a livestock animal and its increasing use as an animal model, knowledge about this relationship in the domestic pig is rare.
Lena Reiske   +3 more
doaj   +1 more source

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