Results 91 to 100 of about 55,807 (381)

N-terminal modification of proteins with o-aminophenols. [PDF]

, 2014
The synthetic modification of proteins plays an important role in chemical biology and biomaterials science. These fields provide a constant need for chemical tools that can introduce new functionality in specific locations on protein surfaces.
Francis, Matthew, Jarman, John, Obermeyer, Allie   +2 more
core   +1 more source

Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease

Aging and Disease, 2016
Flavonoids are known to trigger the intrinsic genetic adaptive programs to hypoxic or oxidative stress via estrogen receptor engagement or upstream kinase activation.
N. Smirnova, N. Kaidery, D. Hushpulian, Ilay Rakhman, A. Poloznikov, V. Tishkov, S. Karuppagounder, I. Gaisina, A. Pekcec, K. Leyen, S. Kazakov, Lichuan Yang, B. Thomas, R. Ratan, I. Gazaryan   +14 more
semanticscholar   +1 more source

Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels

Advanced Functional Materials, EarlyView.
Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard, Max Renner‐Rao, Nahid Hassanpour, Franziska Jehle, Chang‐Sheng Wang, Duy Anh Pham, Daniel J. Jackson, Xavier Banquy, Matthew J. Harrington   +8 more
wiley   +1 more source

Arterio-venous differences in cord levels of catecholamines, glucose, lactate and blood gases [PDF]

, 2016
Norepinephrine (NE) and epinephrine (EPI) levels are higher in cord arterial blood relative to venous blood, consistent with active mechanisms of placental-maternal clearance.
Eisenhofer, Graeme, Hume, Robert, Koh, Daisy K M, Watson, Jennifer, Williams, Fiona L R   +4 more
core   +2 more sources

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists [PDF]

Pharmaceuticals, 2013
Nearly 1% of all clinically used drugs are catecholics, a family of catechol-containing compounds. Using label-free dynamic mass redistribution and Tango β-arrestin translocation assays, we show that several catecholics, including benserazide, catechol, 3-methoxycatechol, pyrogallol, (+)-taxifolin and fenoldopam, display agonistic activity against ...
Deng, Huayun, Fang, Ye
openaire   +3 more sources

Conductive Bonding and System Architectures for High‐Performance Flexible Electronics

Advanced Functional Materials, EarlyView.
This review outlines bonding technologies and structural design strategies that support high‐performance flexible and stretchable electronics. Bonding approaches such as surface‐activated bonding and anisotropic conductive films, together with system‐level architectures including buffer layers and island‐bridge structures, possess distinct mechanical ...
Kazuma Nakajima, Kenjiro Fukuda
wiley   +1 more source

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.

PLoS Pathogens, 2009
Mycobacterium tuberculosis, the etiological agent of TB, possesses a cholesterol catabolic pathway implicated in pathogenesis. This pathway includes an iron-dependent extradiol dioxygenase, HsaC, that cleaves catechols.
Katherine C Yam, Igor D'Angelo, Rainer Kalscheuer, Haizhong Zhu, Jian-Xin Wang, Victor Snieckus, Lan H Ly, Paul J Converse, William R Jacobs, Natalie Strynadka, Lindsay D Eltis   +10 more
doaj   +1 more source

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

Advanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang, Jingjing Fu, Jin Chai, Hongyu Jiang, Fan Chen, Yufei Zhang, Weihao Zhao, Xian Song, Zhihao Zhou, Lingtao Fang, Qiyao Huang, Peng Li, Zijian Zheng   +12 more
wiley   +1 more source

Mixing and matching siderophore clusters: structure and biosynthesis of serratiochelins from Serratia sp. v4 [PDF]

, 2012
Studying the evolutionary history underlying the remarkable structures and biological activities of natural products has been complicated by not knowing the functions they have evolved to fulfill.
Bosello M., Caza M., Challis G. L., Crosa J. H., Ehlert G., Fischbach M. A., Gavin Carr, Gehring A. M., Hera Vlamakis, Hider R. C., Hillson N. J., Hillson N. J., Jon Clardy, Jurkevitch E., Keating T. A., Keating T. A., Lamont I. L., Lazos O., Luke R. K., Maria João Vieira, Marshall C. G., Marshall C. G., Miethke M., Mohammad R. Seyedsayamdost, Pool K., Ratledge C., Roberto Kolter, Sandy M., Sara Cleto, Schwyn B., Seyedsayamdost M. R., Stachelhaus T., Wyckoff E. E.   +32 more
core   +2 more sources

Dual‐Site Ru Single‐Atoms and RuP Nanoclusters on N, P, and B Co‐Doped Porous Carbon for Efficient Alkaline HER and AEM Water Electrolysis

Advanced Functional Materials, EarlyView.
Ru single atoms and RuP nanoclusters are co‐anchored in N, P, and B co‐doped porous carbon nanospheres via in situ carbonization/phosphidation of a boronate polymer precursor. RuP activates water, while nearby Ru single atoms accelerate H2 formation through H* transfer. The catalyst delivers low overpotential and high durability in alkaline HER and AEM
Xiaohong Wang, Juguo Dai, Dongxu Li, Jianghua Wu, Hucheng Fu, Yiting Xu, Xueqiang Qi, Qian Xue, Yanbin Shen, Xiaoqing Pan, Conghui Yuan, Shuifen Xie, Andreu Cabot, Lizong Dai   +13 more
wiley   +1 more source