Results 221 to 230 of about 6,174 (259)
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Toxicology and Applied Pharmacology, 2000
The catechol metabolites of estradiol, 2- and 4-hydroxyestradiol (2-OHE(2) and 4-OHE(2), respectively) are potent signaling molecules and are hypothesized to be central to estrogen-linked carcinogenesis. Methylation by catechol-O-methyltransferase (COMT) is the principal means of catechol estrogen (CE) deactivation in the liver and other tissues.
C E, Garner +3 more
openaire +2 more sources
The catechol metabolites of estradiol, 2- and 4-hydroxyestradiol (2-OHE(2) and 4-OHE(2), respectively) are potent signaling molecules and are hypothesized to be central to estrogen-linked carcinogenesis. Methylation by catechol-O-methyltransferase (COMT) is the principal means of catechol estrogen (CE) deactivation in the liver and other tissues.
C E, Garner +3 more
openaire +2 more sources
Nucleophilic Deoxyfluorination of Catechols
Organic Letters, 2011Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated analogues.
Hiroyuki, Nemoto +2 more
openaire +2 more sources
Journal of Steroid Biochemistry, 1988
Reaction of estrone-3,4-o-quinone with ethanethiol and glutathione leads to the formation of 4-hydroxyestrone-2-thioethers. Incubations of [1-3H]hydroxyestrone with rat liver microsomes and NADPH in the presence of glutathione results in the formation of 4-hydroxyestrone-S-glutathione with no release of tritium in the water indicating GSH addition to C-
Y J, Abul-Hajj, P L, Cisek
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Reaction of estrone-3,4-o-quinone with ethanethiol and glutathione leads to the formation of 4-hydroxyestrone-2-thioethers. Incubations of [1-3H]hydroxyestrone with rat liver microsomes and NADPH in the presence of glutathione results in the formation of 4-hydroxyestrone-S-glutathione with no release of tritium in the water indicating GSH addition to C-
Y J, Abul-Hajj, P L, Cisek
openaire +2 more sources
Selective sensing of catechol based on a fluorescent nanozyme with catechol oxidase activity
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023Nanozymes, an unusual category of nanomaterials possessing enzymatic properties, and have generated considerable interest regarding their application feasibilities on several important fronts. In the present work, an innovative sensing device for catechol was established ground on a fluorescent nanozyme (Cu-BDC-NH2) that exhibited catechol oxidase ...
Le, Wang +5 more
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Complexes of osmium(VI) with catechol and substituted catechols
Journal of the Chemical Society, Dalton Transactions, 1978Osmium tetraoxide reacts with catechols, R(OH)2-o, to give the tris(catecholato)-species [Os(O2R)3] and the polymers [{OsO(O2R)2}n], while in the presence of pyridine or substituted pyridines (L)trans-[OsO2(O2R)L2] complexes are formed. Reaction of cis-[OsO4(OH)2]2– or trans-[OsO2(OH)4]2– with catechols yields salts of trans-[OsO2(O2R)2]2–.
Alastair J. Nielson, William P. Griffith
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Alkylation of catechol with cyclohexene. Novel sterically hindered o-quinones and catechols
Russian Chemical Bulletin, 2020N O Druzhkov +2 more
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