Results 101 to 110 of about 305,262 (317)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
What Is Meditation? Proposing an Empirically Derived Classification System
Meditation is an umbrella term, which subsumes a huge number of diverse practices. It is still unclear how these practices can be classified in a reasonable way. Earlier proposals have struggled to do justice to the diversity of meditation techniques. To
Karin Matko, Peter Sedlmeier
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Cartographies of the mind: Generalization and relevance in cognitive landscapes
The problem of relevance, at individual agent scale – or how we decide what is adequate for our interpretation of the signs we encounter in the world – is a question that keeps reappearing in semiotics and other disciplines concerned with meaning.
Sergio Rodríguez Gómez
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The development of categorization in early childhood: a review
Despite receiving scant attention, the evolution of categorization in early childhood is of central importance, not only in clarifying the child’s understanding of the world but in terms of refining cognitive organization and augmenting the development ...
Owen, K., Barnes, Christopher
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Using different experimental tasks, researchers have pointed to a possible correlation between grammatical gender and classification behaviour. Such effects, however, have been found comparing speakers of a relatively small set of languages.
Luca Vernich +2 more
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Food perception and categorization: From food/no-food to different types of food
The ability to categorize food and nonfood correctly and to distinguish between different foods is essential for our survival. Because of our omnivore nature and because of the food-rich environment in which we live, categorization processes involving ...
Foroni F. +5 more
core +1 more source

