Results 121 to 130 of about 305,262 (317)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Roots, Heads, or Both? Categorizing Turkish Derivational Affixes
Dilbilim Araştırmaları DergisiThe categorization of derivational affixes has received well-deserved attention in Distributed Morphology. In addition to single-categorization views that classify derivational affixes as either roots or heads,a recent proposal argues that such units can
Eniz OĞUZ
doaj +1 more source
Categorization generated by prototypes -- an axiomatic approach [PDF]
We present a model of categorization based on prototypes. A prototype is an image or template of an idealized member of the category. Once a set of prototypes is defined, entities are sorted into categories on the basis of the prototypes they are closest
Ehud Lehrer, Yaron Azrieli
core
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Basic Concepts: A Cognitive Approach
Studia Semiotyczne, 2019 DOI: http://doi.org/10.26333/sts.xxxiii1.09 This article seeks to describe concepts of a special kind, these being ones that count as basic, while at the same time referring to the results of research in logic, the philosophy of language, and ...
Wiesław Walentukiewicz
doaj
Categorization is a core psychological process central to consumer and managerial decision-making. While a substantial amount of research has been conducted to examine individual categorization behaviors, relatively little is known about the group ...
Hamilton, R.W. +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
On The Gradability of Metaphor
Studies in Logic, Grammar and RhetoricMy purpose in this paper is to demonstrate that metaphor should be viewed as a gradable conceptual phenomenon, and to elucidate further the notion of minimal metaphoric mapping between subordinate level concepts dominated by the same basic level category,
Bierwiaczonek Bogusław
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