Results 161 to 170 of about 305,262 (317)
, 2014 This presentation departs from the ongoing debate on the role that institutional categorization plays in the clientization of people within social work and the need for documentation studies about welfare services.
Forssell, Emilia, +2 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interacting Dimensions of Diversity: Cross-Categorization and the Functioning of Diverse Work Groups
We conducted an experiment to show how the interplay between informational diversity and other dimensions of diversity can account for some of the inconsistent effects of informational diversity in previous research.
Dreu, C.K.W. de +3 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
The time course of visual categorization: Electrophysiological evidence from ERP
, 2006 Visual categorization can be derived from interaction between inputting features set (IFS) from outside stimuli and anticipating features set (AFS) from concept, and such interaction can take two forms: match extraction and conflict control.
Li, Hong +3 more
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Improving Bags-of-Words model for object categorization
, 2013 In the past decade, Bags-of-Words (BOW) models have become popular for the task of object recognition, owing to their good performance and simplicity. Some of the most effective recent methods for computer-based object recognition work by detecting and ...
Zhang, Edmond Yiwen, Edmond Yiwen Zhang
core
A Coupled Hidden Markov Model Framework for Measuring the Dynamics of Categorization
We introduce a new framework for measuring the dynamics of category learning using Coupled Hidden Markov Models (CHMMs). The key assumptions of the framework are that people maintain a latent assignment of every stimulus to a category, and that they can ...
Jesus Manuel Villarreal, Michael Lee
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source