Clinical implementation and impact of real-time Cherenkov imaging for treatment verification and patient safety in radiation therapy. [PDF]
Phys Imaging Radiat OncolRobinson A, Tallhamer M.
europepmc +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Prediction of risk of death in severely injured patients: the revised injury severity classification score, version 3 (RISC III). [PDF]
Eur J Trauma Emerg SurgLefering R, Imach S, Bieler D.
europepmc +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Impact of the 2024 Organ Procurement and Transplantation Network Kidney Donor Profile Index Rescoring on Donor Kidney Utilization and Allocation out of Sequence: A one-Year Analysis. [PDF]
Clin TransplantHe S, Thomas CP, Reed AI.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Spiking neural models for decision-making tasks with learning. [PDF]
J Math BiolJaffard S +3 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Survey on the current status of rabies post-exposure prophylaxis clinics construction and the surveillance of rabies-exposed individuals in China, 2022. [PDF]
PLoS Negl Trop DisRen Q +10 more
europepmc +1 more source