Results 131 to 140 of about 169,753,816 (340)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The role of transportation in the spread of Brachyspira hyodysenteriae in fattening farms
BMC Veterinary Research, 2018 Background Direct and indirect contact among animals and holdings are important in the spread of Brachyspira hyodysenteriae. The objective of this study was to investigate the role of slaughterhouse vehicles in spreading B.
Enrico Giacomini +7 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Classica CracoviensiaThe article cites passages from Τέχνη γραμματική which characterise the grammatical category of the noun number (ἀριθμοὶ ὀνομάτων) and define two classes of nouns, i.e.
Hubert Wolanin
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Daily tornado frequency distributions in the United States
Environmental Research Letters, 2014 The authors examine daily tornado counts in the United States over the period 1994–2012 and find strong evidence for a power-law relationship in the distribution frequency.
J B Elsner +3 more
doaj +1 more source
On the category of cocommutative Hopf algebras
, 2019 In [1] we prove that the category of cocommutative Hopf algebras over any field is semi-abelian [2]. The aim of this talk is to give an idea of the proof of this result and to explain some of its consequences.
Sterck, Florence, Category theory 2019
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Proposed multi-signal input fault diagnosis of wind turbine bearing based on glow model
Frontiers in Energy ResearchIn the fault diagnosis, the problem of insufficient fault samples and unbalanced number of fault category samples can occur. In this paper, we used Glow model to supplement the number of wind turbine bearing fault samples to enhance the diagnosis ...
Bin Wang +5 more
doaj +1 more source