The Facilitation of Cognitive Procedures is not Dependent on Maintenance of Declarative Memory Elements. [PDF]
Baranski MFS +4 more
europepmc +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Image classification for a large number of object categories
The release of challenging data sets with ever increasing numbers of object categories isforcing the development of image representations that can cope with multiple classes andof algorithms that are efficient in training and testing. This thesis explores the problem ofclassifying images by the object they contain in the case of a large number of ...
openaire +2 more sources
Considering Deintensification and Deprescribing with Higher HbA1c Targets in Vulnerable Older Adults with Type 2 Diabetes: A Retrospective Database Study. [PDF]
Koto R +3 more
europepmc +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Beyond the tip of the iceberg: quantifying the odds of multidrug-resistance carriers for receiving post-acute follow-up rehabilitation after hospital stay - a real-world study using German data. [PDF]
Kaba HEJ +2 more
europepmc +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A data-driven comparative analysis on citation intents across scientific disciplines. [PDF]
Phan TA, Nam S, Jung JJ.
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Latent Profiles and Dyadic Patterns of Depressive Symptoms in Couples Navigating the Peri-Dialysis Period. [PDF]
Cai D, Wan G, Yang Q, Dai L.
europepmc +1 more source

